Results 61 to 70 of about 36,373 (217)

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

open access: yesAnimal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun   +6 more
wiley   +1 more source

Inventory Replenishment and Transshipment for Distributed Autologous Cell Therapy Manufacturing Networks

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Autologous cell therapy (AuCT) manufacturing networks must balance two competing objectives: reducing cost and improving patient access to time‐sensitive therapy. This study compares three AuCT manufacturing network designs: a centralized network with a single manufacturing facility, a coordinated point‐of‐care (POC) network in which POCs can ...
Zhaowei Li   +3 more
wiley   +1 more source

Variability of Particulate Organic Carbon Stock in the South China Sea With Reference to Profile Structures

open access: yesGeophysical Research Letters
Accurate characterization of particulate organic carbon (POC) stock is essential for understanding regional biological pump processes, yet the roles of vertical structure and integration depth in regulating POC stock variability remain unclear in ...
Teng Li   +9 more
doaj   +1 more source

Cell and Gene Therapies Manufacturing Challenges and Integrated Good Manufacturing Practices Solutions: A Lifecycle Perspective

open access: yesBiotechnology and Bioengineering, EarlyView.
Lifecycle perspective on cell and gene therapy manufacturing challenges and enabling GMP solutions. ABSTRACT Cell and gene therapies (CGTs) are revolutionizing modern medicine; however, making these advanced medicines scalable and readily available to commercial manufacturers worldwide is a major challenge. The number of approved CGT products continues
Rajath Samaga   +2 more
wiley   +1 more source

Seasonal fluxes and age of particulate organic carbon exported from Arctic catchments impacted by localized permafrost slope disturbances

open access: yesEnvironmental Research Letters, 2014
Projected warming is expected to alter the Arctic permafrost regime with potential impacts on hydrological fluxes of particulate organic carbon (POC) and sediment.
Scott F Lamoureux, Melissa J Lafrenière
doaj   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

open access: yesBMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma   +8 more
wiley   +1 more source

Optimal Follow-up of Incidental Pancreatic Cystic Lesions without Worrisome Features: The Follow-up Strategy Is Still Evolving

open access: yesGut and Liver
Background/Aims: Peroral cholangioscopy (POC) has been used to assess intrahepatic duct (IHD) lesions but with a limited role. A new multibending (MB) ultraslim endoscope has been designed to improve POC performance.
Tae Yoon Lee
doaj   +1 more source

Biogeochemical layering and transformation of particulate organic carbon in the Tropical Northwestern Pacific Ocean inferred from δ13C [PDF]

open access: yesOcean Science
Particulate organic carbon (POC) serves as the main carrier of the biological pump and determines its transmission efficiency, yet the transformation processes of POC remain incompletely understood.
D. Tian   +19 more
doaj   +1 more source

Metal nanostructure‐coupled label‐free localized surface plasmon resonance biosensors for rapid and sensitive disease diagnosis

open access: yesBMEMat, EarlyView.
LSPR biosensing enables rapid, sensitive, and low‐sample‐volume detection of biomarkers, with broad applications in diagnosing cancer, infectious, and chronic diseases. Advances in nanostructure design, micro/nanofabrication, and microfluidic integration have expanded the potential of LSPR sensors in biomedical diagnostics.
Zhaoxin Geng   +4 more
wiley   +1 more source

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

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