Results 41 to 50 of about 81,433 (222)

A Phase 2 Trial of Hydroxychloroquine in Individuals at Risk for Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Individuals with serum elevations of anti–cyclic citrullinated peptide (anti‐CCP) antibodies are at increased risk for future rheumatoid arthritis (RA). No pharmacologic interventions have been approved for the prevention of RA in such at‐risk individuals.
Kevin D. Deane, Christopher C. Striebich, Marie L. Feser, James R. O'Dell, Judith A. James, Jeffrey A. Sparks, John M. Davis III, Jonathan Graf, Maureen A. McMahon, Elizabeth B. Solow, Lindsy J. Forbess, Athan Tiliakos, Elena Schiopu, Maria I. Danila, Diane L. Horowitz, Jonathan Kay, Colin D. Strickland, Joel M. Guthridge, Cristina Arriens, Jennifer M. Grossman, M. Kristen Demoruelle, Elizabeth A. Bemis, Ashley Frazer‐Abel, Chelsie L. Fleischer, David A. Fox, Ted R. Mikuls, Melissa Greenleaf, Kate York, Sarah Walker, Lynette Keyes‐Elstein, Margie Byron, Janel Fedler, Ellen A. Goldmuntz, V. Michael Holers   +33 more
wiley   +1 more source

First Description of the Female of the Trinidadian Theraphosine Spinosatibiapalpus trinitatis (Pocock, 1903) (Araneae: Theraphosidae)

Taxonomy, 2021
The hitherto unknown female of the theraphosine Spinosatibiapalpus trinitatis (Pocock, 1903) is herein described based on the paralectotype series of the schismatotheline Neoholothele incei (F. O. Pickard-Cambridge, 1899) housed in the collections of the
Danniella Sherwood, José Paulo Leite Guadanucci, Ray Gabriel   +2 more
doaj   +1 more source

Handling Covariates in the Design of Clinical Trials

, 2011
There has been a split in the statistics community about the need for taking covariates into account in the design phase of a clinical trial. There are many advocates of using stratification and covariate-adaptive randomization to promote balance on ...
Rosenberger, William F., Sverdlov, Oleksandr   +1 more
core   +1 more source

Efficacy and Safety of Subcutaneous Anifrolumab in Systemic Lupus Erythematosus: A Randomized, Phase 3 Study

Arthritis &Rheumatology, EarlyView.
Objective The multinational, phase 3, double‐blind, placebo‐controlled TULIP‐SC trial evaluated the efficacy and safety of subcutaneous anifrolumab in adults who have moderate to severe systemic lupus erythematosus (SLE) activity, despite receiving standard therapy. Methods Adults with SLE received subcutaneous anifrolumab 120 mg or placebo once weekly
Susan Manzi, Ian N. Bruce, Eric F. Morand, Richard Furie, Yoshiya Tanaka, Kenneth C. Kalunian, Anca Askanase, Patricia Puzio, Emon Khan, Jenny Wissmar, Michael Song, Catharina Lindholm, for the TULIP‐SC investigators   +12 more
wiley   +1 more source

Does aspirin detract from the benefits of mineralocorticoid receptor antagonists in patients with heart failure and a reduced left ventricular ejection fraction? Probably! [PDF]

, 2017
No abstract ...
Aspirin Myocardial Infarction Study Research Group, Baigent, Baigent, Bonaca, Chin, Cleland, Cleland, Cleland, Cleland, Cleland, Cleland, Gelder, Homma, Lewis, Massie, Meune, Michel, Pitt, Pitt, Silva, Solomon, Tweeddale, Zannad, Zannad   +23 more
core   +1 more source

The spread of non‐native species

Biological Reviews, EarlyView.
ABSTRACT The global redistribution of species through human agency is one of the defining ecological signatures of the Anthropocene, with biological invasions reshaping biodiversity patterns, ecosystem processes and services, and species interactions globally.
Phillip J. Haubrock, Ali Serhan Tarkan, Irene Martín‐Forés, Stelios Katsanevakis, Ronaldo Sousa, Ismael Soto, Andy J. Green, Antonín Kouba, Teun Everts, Victoria Dominguez Almela, Nadège Belouard, Cang Hui, Jamie Bojko, Victor Deklerck, Margaux Boeraeve, Franz Essl, J. Robert Britton   +16 more
wiley   +1 more source

Wales, the Enlightenment and the New British History [PDF]

, 2013
There is no electronic version of this article.PostprintPeer ...
Kidd, Colin Craig
core  

Association of COPD with adverse outcomes in heart failure patients with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 799-808, April 2025.
Abstract We performed a systematic review and meta‐analysis to detect the impact of chronic obstructive pulmonary disease (COPD) on the prognosis of heart failure patients with preserved ejection fraction (HFpEF). We systematically screened eligible literature from three electronic databases, PubMed, EMBASE and Cochrane Library, up to April 2023.
Shuo Xu, Zhenbang Gu, Wengen Zhu, Shenghui Feng   +3 more
wiley   +1 more source

Performing public credit at the eighteenth-century Bank of England [PDF]

, 2019
Much is known about the negotiation of personal credit relationships during the eighteenth century. It has been noted how direct contact and observation allowed individuals to assess the creditworthiness of those with whom they had financial connections ...
Abramson, Acemoglu, Acres, Anne L. Murphy, Binney, Booker, Bowen, Brantlinger, Carey, Clapham, Cobbett, Defoe, Defoe, Defoe, Defoe, Dickson, Fielding, Finn, Giuseppi, Kynaston, Leemans, Macdonald, Major, Malton, Mitchell, Mortimer, North, Roxburgh, Stasavage, Supple   +29 more
core   +3 more sources

A preliminary survey and range extension of millipedes species introduced in Brazil (Myriapoda, Diplopoda)

Papéis Avulsos de Zoologia, 2021
The present study provides historical and new records of the introduced millipedes species in Brazil, Oxidus gracilis (C.L. Koch, 1847), Orthomorpha coarctata (Saussure, 1860) (Paradoxosomatidae), Prosopodesmus jacobsoni Silvestri, 1910 (Haplodesmidae ...
Luiz Felipe Moretti Iniesta, Rodrigo Salvador Bouzan, Patrícia Elesbão da Silva Rodrigues, Thais Melo de Almeida, Ricardo Ott, Antonio Domingos Brescovit   +5 more
doaj   +1 more source