Results 311 to 320 of about 64,667 (338)
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Modes of podocyte death in diabetic kidney disease: an update

JN. Journal of Nephrology (Milano. 1992), 2022
Anni Jiang, A. Song, Chun Zhang
semanticscholar   +1 more source

Podocytes, glucose and insulin

Current Opinion in Nephrology and Hypertension, 2010
In the last decade the importance of the podocyte in maintaining the integrity of the glomerular filtration barrier and prevention of albuminuria has become obvious. The leading cause of renal failure in the developed world is diabetic nephropathy. This has a defined natural history of progressive albuminuria.
Welsh, Gavin I, Coward, Richard J M
openaire   +3 more sources

The role of podocytes in proteinuria

Nephrology, 2007
SUMMARY:  Glomerular visceral epithelial cells, also known as podocytes, are highly specialized epithelial cells that cover the outer layer of the glomerular basement membrane. Podocytes consist of cell bodies, major processes and foot processes (FP) of neighbouring cells, with the filtration slits bridged by the slit membrane between them.
Katsuhiko, Asanuma   +4 more
openaire   +2 more sources

miR‐15b‐5p ameliorated high glucose‐induced podocyte injury through repressing apoptosis, oxidative stress, and inflammatory responses by targeting Sema3A

Journal of Cellular Physiology, 2019
Podocyte damage is a hallmark of diabetic nephropathy (DN). Accumulating evidence indicates that microRNAs play important roles in the DN pathogenesis. This study aimed to explore the possible roles and underlying mechanisms of miR‐15b‐5p on high glucose
Yanqin Fu   +5 more
semanticscholar   +1 more source

Podocytes: Gaining a foothold

Experimental Cell Research, 2012
In an attempt to understand the basis of glomerular disease, significant progress has been made in understanding the mechanisms that determine podocyte development and the maintenance of podocyte health. This review examines recent advances in this area focusing on the podocyte intercellular junction, actin cytoskeletal dynamics, and determinants of ...
Puneet, Garg, Lawrence B, Holzman
openaire   +2 more sources

cAMP pathway in podocytes

Microscopy Research and Technique, 2002
AbstractPodocytes possess receptors for a variety of hormones. The following receptors whose stimulation results in increased cAMP levels have been detected in podocytes: adrenergic β2 receptor, dopamine D1 receptor, prostaglandin IP and EP4 receptors, and parathyroid hormone (PTH)/PTH‐related protein (PTHrP) receptor. Besides activating protein kinase
Nicole, Endlich, Karlhans, Endlich
openaire   +2 more sources

Podocyte polarity signalling

Current Opinion in Nephrology and Hypertension, 2009
The glomerular filtration barrier is a unique structure characterized by a specialized three-dimensional framework of podocytes. This review is aimed at describing the latest advances made in the understanding of polarity signalling pathways regulating the formation and the maintenance of the complex podocyte architecture.Podocytes are composed of a ...
Simons, Matias   +2 more
openaire   +3 more sources

Podocyte regeneration: who can become a podocyte?

The American journal of pathology, 2013
This Commentary highlights the article by Pippin et al that showed that renin lineage cells may enhance glomerular regeneration by serving as progenitors for glomerular epithelial cells in glomerular disease characterized by podocyte depletion.
Florian, Grahammer   +2 more
openaire   +1 more source

Foamy podocytes

American Journal of Kidney Diseases, 2003
Neil, Renwick   +7 more
openaire   +2 more sources

MiR-21-5p in macrophage-derived extracellular vesicles affects podocyte pyroptosis in diabetic nephropathy by regulating A20

Journal of Endocrinological Investigation, 2020
X. Ding   +11 more
semanticscholar   +1 more source

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