Urinary Nephrin: A Potential Biomarker of Early Glomerular Injury in a Cohort of Pregnant Women Attending Routine Antenatal Care Services. [PDF]
Introduction: Glomerular injury may occur during pregnancy as a consequence of systemic disease and pregnancy‐related medical complications. While urinary nephrin has been shown to provide early identification of preeclampsia (PE) in high‐risk pregnancies, the role of urinary nephrin in determining glomerular injury in pregnant women is yet to be ...
Mesfine BB +5 more
europepmc +2 more sources
Background. Diabetes mellitus (DM) is marked by oxidative stress, inflammation, and vascular dysfunction that caused diabetic nephropathy that resulted in end‐stage renal disease (ESRD). Vascular dysfunction is characterized by an imbalance in vasoconstrictor and vasodilator agents which underlies the mechanism of vascular injury in DM.
Wiwit A. W. Setyaningsih +5 more
wiley +1 more source
Analysıs of Urınary Albumın and Urınary Synaptopodın Levels in Type 2 Dıabetes Mellıtus Subjects [PDF]
Hyperglycemia from diabetes mellitus affects many body organs and interferes with normal function. Kidney function decreased in approximately one-third of patients with diabetes mellitus before the development of albuminuria.
Esa, Tenri +6 more
core +2 more sources
The Effect of Pravastatin on Expression of ENOS, ET-1, Nephrine, VEGF, TNF-Α, And IL-10 on Tissue Kidney Rat Model of Preeclampsia [PDF]
Background: Preeclampsia is known as a disease originating from placental and maternal dysfunction. Placental dysfunction can cause cellular, molecular, immunological, and vascular changes.
Bambang Rahardjo, Melinda Puspitasari, Maria Ulfa Nur Hidayanti, Jashinta F Tahun, Anin Andriani, Diadjeng Setya Wardani, Sutrisno, I Wayan Agung Indrawan
core +2 more sources
Increased podocyturia in pregnant women compared to non‐pregnant women [PDF]
AbstractAimHyperfiltration is a cause of podocyturia and occurs physiologically in the kidney of pregnant women. Podocyturia is increased in preeclamptic pregnancies, but it is unclear whether there is also any increase in uncomplicated pregnancies.
Itsuko Furuta +8 more
openaire +7 more sources
A comparison of podocyturia, albuminuria and nephrinuria in predicting the development of preeclampsia: a prospective study. [PDF]
Preeclampsia, a hypertensive multisystem disease that complicates 5-8% of all pregnancy, is a major cause for maternal and fetal mortality and morbidity.
Belinda Jim +7 more
doaj +1 more source
Increased urinary CD80 excretion and podocyturia in Fabry disease [PDF]
Certain glomerulopathies are associated with increased levels of CD80 (B7-1). We measured the urinary excretion of CD80, podocyturia and proteinuria in controls and in subjects with Fabry disease either untreated or on enzyme replacement therapy (ERT).
Hernán Trimarchi +16 more
openaire +2 more sources
Progress of research on dyslipidemia accompanied by nephrotic syndrome
Abstract Nephrotic syndrome is a relatively common clinical disease. Associated dyslipidemia is a risk factor for the occurrence and development of cardiovascular and renal diseases that might gradually develop into atherosclerosis, glomerulosclerosis or tubulointerstitial injury.
Min Tao +3 more
wiley +1 more source
Antiproteinuric action of amiloride in paediatric patient with corticoresistant nephrotic syndrome
Introduccion: In nephrotic syndrome, increased podocyturia accompanies pathologic proteinuria. The therapeutic regimen with enalapril, losartan and amiloride could reduce both variables.
Miguel Liern +3 more
doaj +1 more source
Podocyturia: why it may have added value in rare diseases. [PDF]
Fabry disease is an inherited lysosomal disease in which defects in the GLA gene lead to α-galactosidase-A deficiency, and accumulation of glycosphingolipids, including lyso-Gb3, a podocyte stressor. Therapy is available as enzyme replacement therapy and, for some patients, the chaperone migalastat.
Sanchez-Niño MD +4 more
europepmc +5 more sources

