Results 61 to 70 of about 499 (150)

Comparative Prognostic Value of Podocyturia Versus Microalbuminuria in Predicting Diabetic Nephropathy Progression: A Meta-Analysis [PDF]

Background: Diabetic nephropathy represents the primary etiology of end-stage renal disease globally. Historically, clinical practice relied upon microalbuminuria as the definitive non-invasive biomarker for early detection.
Harnavi Harun, Deka Viotra, Drajad Priyono, Bayu Arief Hartanto   +3 more
core   +2 more sources

Yi Qi Qing Re Gao Attenuates Podocyte Injury and Inhibits Vascular Endothelial Growth Factor Overexpression in Puromycin Aminonucleoside Rat Model

Evidence-Based Complementary and Alternative Medicine, Volume 2014, Issue 1, 2014., 2014
Proteinuria is the hallmark of chronic kidney disease. Podocyte damage underlies the formation of proteinuria, and vascular endothelial growth factor (VEGF) functions as an autocrine/paracrine regulator. Yi Qi Qing Re Gao (YQQRG) has been used to treat proteinuria for more than two decades.
Yongli Zhan, Liping Yang, Yumin Wen, Huijie Liu, Haojun Zhang, Bin Zhu, Wenbing Han, Yanting Gu, Xueyan Sun, Xi Dong, Tingting Zhao, Huixia Ma, Ping Li, Yoshiji Ohta   +13 more
wiley   +1 more source

Assessment of Urinary Osteopontin in Association with Podocyte for Early Predication of Nephropathy in Diabetic Patients

Disease Markers, Volume 2014, Issue 1, 2014., 2014
Objectives. Microalbuminuria has been clinically used for noninvasive evaluation of renal dysfunctions. However, it is a nonspecific marker of diabetic nephropathy (DN). Methods. This study was conducted from March 2012 to April 2013 at Biochemistry Unit, King Fahd Medical Research Center (KFMRC).
Abdulrahman L. Al-Malki, Vincent Sapin
wiley   +1 more source

Soluble Fas and the −670 Polymorphism of Fas in Lupus Nephritis

International Journal of Nephrology, Volume 2014, Issue 1, 2014., 2014
This study was performed to clarify the role of soluble Fas (sFas) in lupus nephritis (LN) and establish a potential relationship between LN and the −670 polymorphism of Fas in 67 patients with systemic lupus erythematosus (SLE), including a subset of 24 LN patients with proteinuria. Additionally, a group of 54 healthy subjects (HS) was included.
Juan José Bollain-y-Goytia, Mariela Arellano-Rodríguez, Felipe de Jesús Torres-Del-Muro, Leonel Daza-Benítez, José Francisco Muñoz-Valle, Esperanza Avalos-Díaz, Rafael Herrera-Esparza, Danuta Zwolinska   +7 more
wiley   +1 more source

Amiloride as an Alternate Adjuvant Antiproteinuric Agent in Fabry Disease: The Potential Roles of Plasmin and uPAR

Case Reports in Nephrology, Volume 2014, Issue 1, 2014., 2014
Patients with Fabry disease present a higher risk of cardiovascular and kidney morbidity. We present a patient with a past history of biopsy‐proven Fabry disease and stage 3 chronic kidney disease. Proteinuria partially dropped from 6.8 g/day to 2.1 g/day despite an aggressive regime which consisted of low‐salt diet, agalsidase beta infusions, dual ...
H. Trimarchi, M. Forrester, F. Lombi, V. Pomeranz, M. S. Raña, A. Karl, J. Andrews, Alfons Segarra   +7 more
wiley   +1 more source

Podocyturia assay. [PDF]

, 2014
Hoechst nuclear staining (blue); podocin antibody followed by a secondary fluorescein isothiocyanate-labeled antibody (green).
Steven J. Wagner (541944), Patrick D. Fitz-Gibbon (541945), Brian C. Brost (541947), Angelica T. Garrett (541942), Carl H. Rose (541948), Wendy M. White (541941), Kim A. Butters (541946), Vesna D. Garovic (541950), Iasmina M. Craici (541943), Joseph P. Grande (541949)   +9 more
core   +1 more source

A Compendium of Urinary Biomarkers Indicative of Glomerular Podocytopathy

Pathology Research International, Volume 2013, Issue 1, 2013., 2013
It is well known that glomerular podocyte injury and loss are present in numerous nephropathies and that the pathophysiologic consecution of disease hinges upon the fate of the podocyte. While multiple factors play a hand in glomerulopathy progression, basic logic lends that if one monitors the podocyte’s status, that may reflect the status of disease.
Miroslav Sekulic, Simona Pichler Sekulic, Piero Tosi   +2 more
wiley   +1 more source

Therapy with atorvastatin versus rosuvastatin reduces urinary podocytes, podocyte-associated molecules, and proximal tubule dysfunction biomarkers in patients with type 2 diabetes mellitus: a pilot study

Renal Failure, 2017
Background: Diabetic nephropathy is a severe complication of Type 2 diabetes. Tubular lesions may play an important role in its early stages. The aim of our study was to determine if atorvastatin protects the podocytes and the proximal tubule in patients
Adrian Vlad, Mihaela Vlad, Ligia Petrica, Sorin Ursoniu, Florica Gadalean, Roxana Popescu, Daliborca Vlad, Victor Dumitrascu, Gheorghe Gluhovschi, Cristina Gluhovschi, Silvia Velciov, Flaviu Bob, Petru Matusz, Alina Secara, Anca Simulescu, Dragos Catalin Jianu   +15 more
doaj   +1 more source

Urinary Podocyte Loss Is Increased in Patients with Fabry Disease and Correlates with Clinical Severity of Fabry Nephropathy - Fig 3 [PDF]

, 2016
(A) Comparison of podocyturia in healthy subjects and Fabry patients. Fabry patients had significantly more urine podocytes (p = 0.001) per g creatinine (UPodo/g Cr).
Jonathan A. Jefferson (3590033), C. Ronald Scott (1317870), Michael Mauer (437377), Jeffrey Pippin (271777), Eric Wallace (3590024), Brent Fall (3590030), Stuart Shankland (2808961), David Warnock (3590027), Behzad Najafian (299389)   +8 more
core   +1 more source

Is there a role for urinary podocyte excretion assessment in lupus nephritis? [PDF]

, 2016
Objective To establish the occurrence and intensity of podocyturia and its relation to grade of disease activity, as defined by clinical and laboratory criteria. Methods Prospective, cross-sectional study involving 50 patients with lupus nephritis and 29
Sabino, Amelia Rodrigues Pereira [UNIFESP], Nishida, Sonia Kiyomi [UNIFESP], Mansur, Juliana Busato [UNIFESP], Kirsztajn, Gianna Mastroianni [UNIFESP]   +3 more
core   +1 more source