Results 131 to 140 of about 19,338 (290)
Development of Core-Fucose-Deficient Humanized and Chimeric Anti-Human Podoplanin Antibodies.
Podoplanin (PDPN), a 36-kDa type I transmembrane O-glycoprotein, is expressed in normal cells, including renal epithelial cells (podocytes), lymphatic endothelial cells, and pulmonary type I alveolar cells, and in cancer cells, including brain tumors and
M. Kaneko +11 more
semanticscholar +1 more source
In this issue of JEM, Rana et al. (https://doi.org/10.1084/jem.20190689) report that adipose tissue multipotent stromal cells (MSCs) provide multifaceted support for adipose tissue-resident ILC2s through contact-mediated proliferation and IL-33-mediated ...
Locksley, Richard M +1 more
core +1 more source
Bone marrow-derived cells are implicated as a source of lymphatic endothelial progenitors in human breast cancer. [PDF]
Bone marrow-derived endothelial progenitor cells (EPCs) infiltrate into sites of neovascularization in adult tissues and mature into functional blood endothelial cells (BECs) during a process called vasculogenesis. Human marrow-derived EPCs have recently
Bron, S. +7 more
core +2 more sources
Whole carcass diets: a role for fibre in gastrointestinal health of cheetahs? [PDF]
This study was undertaken to test the hypothesis that altered podocyte slit protein nephrin distribution is associated with disturbed polarity protein expressions in podocytes from preeclampsia (PE).
Depauw, Sarah +6 more
core +2 more sources
An important role of podoplanin in hair follicle growth
Podoplanin (PDPN) is a glycoprotein that is expressed by various cell types, including keratinocytes, fibroblasts, and lymphatic endothelial cells. We found that PDPN is expressed in the hair follicle (HF) keratinocyte region and HF stem cell area during the late anagen phase but not during the telogen phase in mice.
Michael Detmar +8 more
openaire +5 more sources
Tertiary lymphoid structures in renal cell carcinoma exert immunoregulatory effects in the immune microenvironment by influencing local anti‐tumour immune responses, thereby affecting immunotherapy efficacy and prognosis. Abstract In the tumour microenvironment (TME) of renal cell carcinoma (RCC), tertiary lymphoid structures (TLS) play a crucial role ...
Lin Yang +9 more
wiley +1 more source
PMab-213: A Monoclonal Antibody for Immunohistochemical Analysis Against Pig Podoplanin.
Podoplanin (PDPN) is known to be expressed in normal tissues, including lymphatic endothelial cells, renal podocytes, and type I lung alveolar cells. Monoclonal antibodies (mAbs) against human, mouse, rat, rabbit, dog, cat, and bovine PDPN have already ...
Y. Kato +9 more
semanticscholar +1 more source
CLEC-2-dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP [PDF]
The present results demonstrate that platelet adhesion and activation on CLEC-2 ligands or LECs is maintained in the presence of PGI2 and ...
Bazou +27 more
core +1 more source
Keratinocyte-Expressed Podoplanin is Dispensable for Multi-Step Skin Carcinogenesis
Podoplanin is a small transmembrane mucin-like glycoprotein that plays a crucial role in the development of the lung, heart and lymphatic vascular system.
Marko Sesartić +3 more
doaj +1 more source
Podoplanin associates with CD44 to promote directional cell migration [PDF]
This article is under an Attribution–Noncommercial–Share Alike 3.0 Unported Creative Commons License.-- et al.Podoplanin is a transmembrane glycoprotein up-regulated in different human tumors, especially those derived from squamous stratified epithelia (
Fernández-Muñoz, Beatriz +5 more
core +2 more sources

