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PMab-44 Detects Bovine Podoplanin in Immunohistochemistry
Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, 2016Podoplanin (PDPN)/Aggrus is a type I transmembrane O-glycoprotein, which is expressed in several normal tissues including podocytes of kidney and lymphatic endothelial cells. PDPN activates platelet aggregation by binding to C-type lectin-like receptor-2 (CLEC-2) on platelet; however, only bovine PDPN (bovPDPN) does not possess the platelet-aggregating
Hiroharu Oki +10 more
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Development of Monoclonal Antibody 281-mG2a-f Against Golden Hamster Podoplanin.
Monoclonal antibodies in immunodiagnosis and immunotherapy, 2022Ren Nanamiya +10 more
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Blocking podoplanin inhibits platelet activation and decreases cancer-associated venous thrombosis.
Thrombosis Research, 2021Xia Wang +9 more
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The role of podoplanin in tumor progression and metastasis.
Anticancer research, 2009In the last decade, much data has been generated concerning the molecular mechanisms of lymphangiogenesis and its significance in pathological conditions. This was mainly due to the discovery of lymphatic endothelial cell (LEC)-specific markers, such as vascular endothelial growth factor receptor-3 (VEGFR-3), LYVE-1, Prox-1 and podoplanin.
RAICA M, CIMPEAN A. M, RIBATTI, Domenico
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