Results 131 to 140 of about 2,291,402 (391)

Point of Care Diagnosis of Multiple Schistosome Parasites: Species-specific DNA Detection in Urine by Loop-mediated Isothermal Amplification (LAMP) [PDF]

, 2017
Schistosomes are easily transmitted and high chance of repeat infection, so if control strategies based on targeted mass drug administration (MDA) are to succeed it is essential to have a test that is sensitive, accurate and simple to use.
Anyan, William K., Bosompem, Kwabena M., Lodh, Nilanjan, Mikita, Kei, Otchere, Joseph, Quartey, Joseph K., Shiff, Clive J.   +6 more
core   +2 more sources

External Quality Assessment (EQA) for SARS-CoV-2 RNA Point-of-Care Testing in Primary Healthcare Services: Analytical Performance over Seven EQA Cycles

Diagnostics
In April 2020, the Aboriginal and Torres Strait Islander COVID-19 Point-of-Care (POC) Testing Program was initiated to improve access to rapid molecular-based SARS-CoV-2 detection in First Nations communities.
Susan J. Matthews, Kelcie Miller, Kelly Andrewartha, Melisa Milic, Deane Byers, Peter Santosa, Alexa Kaufer, Kirsty Smith, Louise M. Causer, Belinda Hengel, Ineka Gow, Tanya Applegate, William D. Rawlinson, Rebecca Guy, Mark Shephard   +14 more
doaj   +1 more source

Point-of-Care Diagnostics

, 2014
Rapid tests that are low-cost and portable are the first line of defence in healthcare systems. Dipstick and lateral-flow are the two universal assay formats as they are lightweight and compact, and provide qualitative results without external instrumentation.
openaire   +2 more sources

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

FEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai, Richard J. McDowell, Robert J. Lucas   +2 more
wiley   +1 more source

Lipid droplet detection by the cavity perturbation method [PDF]

, 2011
There are currently no point-of-care diagnosis strategies available to indicate the presence of neoplasmic growth. This research aims to develop a novel diagnostic strategy based on detecting TAG accumulation in cells.
A I Al-Shamma'a, A Mason, C E Rolph, G Bond, Montgomery G A, R T Blakey, Rudan-Tasič D, Wyld L   +7 more
core   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Point of care tests for sexually transmitted infections (STIs) [PDF]

A number of clinical/disease areas have been prioritised by the Technology Strategy Board (TSB) and Department of Health (DH) for the DIIA Innovation Platform.
Osipenko, Leeza, Szczepura, Ala
core  

Crisis and Challenges in the Health Care System: A Personal Point of View [PDF]

, 1989
Dan Michaeli
openalex   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

FEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile, Daniela Ratto, Giorgia Rastelli, Ottavia Eleonora Ferraro, Caterina Temporini, Sunil Kumar, Simona Boncompagni, Paola Rossi, Monica Canepari   +8 more
wiley   +1 more source

Process of designing robust, dependable, safe and secure software for medical devices: Point of care testing device as a case study [PDF]

, 2013
This article has been made available through the Brunel Open Access Publishing Fund.Copyright © 2013 Sivanesan Tulasidas et al. This paper presents a holistic methodology for the design of medical device software, which encompasses of a new way of ...
Balachandran, W, Craw, P, Gkatzidou, V, Hudson, C, Mackay, R, Tulasidas, S   +5 more
core   +3 more sources