Results 301 to 310 of about 2,291,402 (391)

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

A genetically encoded biosensor for point-of-care and live-cell detection of D-2-hydroxyglutarate. [PDF]

Nat Commun
Liu Y, Kang Z, Xu R, Hou S, Gong L, Guo L, Gao K, Xu X, Tan X, Xiao D, Zhang W, Wang G, Ou S, Hu J, Liu J, Lü C, Ma C, Xu P, Gao C.   +18 more
europepmc   +1 more source

Microchip Electrophoresis System "MCE-2010" : μTAS Technology for POCT(<Special Issue>Micro-Machine Technology and Point of Care Testing (POCT))

, 2002
H. Nakanishi
openalex   +2 more sources

CD9‐association with PIP2 areas is regulated by a CD9 salt bridge

FEBS Open Bio, EarlyView.
The tetraspanin CD9 has an intracellular salt bridge. If CD9 opens, open‐CD9 moves from PIP2‐rich areas to regions populated by its interaction partner EWI‐2. Hence, the state of the salt bridge regulates the distribution of CD9 and by this CD9‐EWI‐2 complex formation.
Yahya Homsi, Sara C. Konopka, Thorsten Lang   +2 more
wiley   +1 more source

Towards Automated Testing of Kynurenine for Point-of-Care Metabolomics. [PDF]

Methods Protoc
Bhattacharyya D, LeVatte MA, Wishart DS.
europepmc   +1 more source

Characterization of WAC interactions with R2TP and TTT chaperone complexes linking glucose and glutamine availability to mTORC1 activity

FEBS Open Bio, EarlyView.
TTT and R2TP chaperone complexes are required for the assembly and activation of mTORC1. WAC directly interacts with components of TTT, R2TP, and mTORC1, and these interactions are affected by the availability of glucose and glutamine, correlating with changes in mTORC1 activity.
Sofía Cabezudo, Natalia Cuervo, Carmen García‐Martín, Andrés López‐Perrote, Clara Reglero, Adrián Maqueda‐Real, Ana González‐Corpas, Marina Serna, Diego Megías, Alejo Efeyan, Solip Park, Oscar Llorca   +11 more
wiley   +1 more source

Point-of-Care Ultrasound Diagnosis of Left Ventricular Thrombus: A Case Series. [PDF]

Cureus
Wen TH, Mitina A, Coneybeare D.
europepmc   +1 more source

Ro 31‐8220 suppresses bladder cancer progression via enhancing autophagy in vitro and in vivo

FEBS Open Bio, EarlyView.
The pan‐protein kinase C inhibitor Ro‐31‐8220 demonstrates potent anti‐bladder cancer effects both in vitro and in vivo by suppressing migration/invasion, inducing apoptosis and crucially activating autophagy, where blocking autophagy with chloroquine reduces its cell‐killing efficacy, suggesting its promise as a novel therapeutic candidate requiring ...
Shengjun Fu, Yan Tao, Shan Wu, Yuwen Gong, Youli Zhao, Shaomin Niu, Hui Cheng, You Mu, Na Xu, Ying Wang, Jianzhong Lu, Shanhui Liu, Lanlan Li   +12 more
wiley   +1 more source

Point-of-care ultrasound competency of doctors working in Cape Town emergency departments. [PDF]

S Afr Fam Pract (2004)
Ferreira K, Hendrikse C, Zaayman H, Erasmus E, Van Hoving DJ.   +4 more
europepmc   +1 more source