Results 91 to 100 of about 6,659,408 (317)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Advancing Point-of-Care (PoC) Testing Using Human Saliva as Liquid Biopsy

open access: yes, 2017
Salivary diagnostics is an emerging field for the encroachment of point of care technology (PoCT). The necessity of the development of point-of-care (PoC) technology, the potential of saliva, identification and validation of biomarkers through salivary ...
Faris Yahya Ibrahim Asiri   +3 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Point of care: New connectivity standards and novel technologies in intensive care

open access: yes, 2022
S.175-185About two decades ago, heart and liver transplant centres initiated point-of-care (POC) esting to meet the requirements of accelerated medical decision making.
Mell, J.   +4 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The remodelling of patient care pathway for e-health

open access: yes, 2009
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The interdependencies within the health care system are seldom taken into account prior to implementation of e-health projects, and there tends to be little
Jones, Karen
core  

Sensor-as-a-service: convergence of Sensor aNAlytic Point Solutions (SNAPS) and Pay-A-Penny-Per-Use (PAPPU) paradigm as a catalyst for democratization of healthcare in underserved communities

open access: yes, 2020
In this manuscript, we discuss relevant socioeconomic factors for developing and implementing Sensor aNAlytic Point Solutions (SNAPS) as point-of-care tools to serve impoverished communities.
Datta, Shoumen Pa   +36 more
core   +1 more source

Comparison between the analytical sensitivity and clinical performance of two cobas SARS-CoV-2 tests based on high-throughput and point-of-care systems. [PDF]

open access: yesBiomedicine (Taipei), 2022
Lin TH   +9 more
europepmc   +1 more source

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