Results 231 to 240 of about 3,351,259 (336)

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Practical Coagulation Management in Liver Transplantation Through Point-of-Care Analysis Using the TEG 6s Global Hemostasis System in Japan

Muneyuki Matsumura, Kengo Sasaki, Kazuaki Tokodai, Koji Miyazawa, Atsushi Fujio, Hiroyuki Ogasawara, Michiaki Unno, Takashi Kamei   +7 more
openalex   +2 more sources

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Better than nothing, far from perfect: hospital and healthcare system leaders' perspectives on health information exchanges. [PDF]

JAMIA Open
Turbow SD, Vaughan CP, Ali MK, Clevenger CK, Perkins MM.   +4 more
europepmc   +1 more source

ICU_POC: AN EMR-BASED POINT OF CARE SYSTEM DESIGN FOR THE INTENSIVE CARE UNIT

, 2017
Chika Cornelia Emeka-Nweze
openalex   +1 more source

Microchip Electrophoresis System "MCE-2010" : μTAS Technology for POCT(<Special Issue>Micro-Machine Technology and Point of Care Testing (POCT))

, 2002
H. Nakanishi
openalex   +2 more sources

Actin dynamics controlled by IqgC, a RasGAP at the crossroads between the IQGAP and fungal GAP1 families

FEBS Open Bio, EarlyView.
IqgC is a RasGAP from Dictyostelium discoideum. IqgC binds RasG via its RasGAP domain and deactivates it on macroendocytic cups, thereby suppressing the uptake of fluid and particles. IqgC has a positive effect on cell‐substratum adhesion, and its RGCt domain is required for recruitment to ventral foci.
Vedrana Filić, Darija Putar, Lucija Mijanović, Igor Weber   +3 more
wiley   +1 more source

Feasibility of a 30-Minute Sample-to-Answer Chlamydia Trachomatis, Neisseria Gonorrhea, and Trichomonas Vaginalis Multiplex Test on a Rapid Molecular Point-of-Care System* [PDF]

Brenda Nguyen, Mary T. Pryce, Ernest T. Parker, Jing Liang, Wei Chen, Christopher S. Crowley, Andrew Green, Wu B   +7 more
openalex   +1 more source

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

FEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini, Nicolò Antonelli, Gianluca Molla   +2 more
wiley   +1 more source

Inflammation and suicide risk in adolescents with self-injury: Expanding the role of mental health nursing. [PDF]

World J Psychiatry
Anastasi G.
europepmc   +1 more source