Results 241 to 250 of about 3,351,259 (336)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Deep Learning–Based Classification of PPG-Derived Arterial Stiffness for Embedded Point-of-Care Systems

Munishamaiah Krishna
openalex   +2 more sources

UnitedXR Europe 2025: Aligning Health Care Extended Reality.

J Med Internet Res
Costa JF.
europepmc   +1 more source

Aptamer-Based Biosensors for Point-of-Care Diagnostics. [PDF]

Biosensors (Basel)
Díaz-Fernández A.
europepmc   +1 more source

Systems and methods for point-of-care positron emission tomography

, 2023
Yuan‐Chuan Tai
openalex   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Untold Stories of Black and Racialized Immigrants with Disabilities During COVID-19 in the Greater Toronto and Hamilton Area. [PDF]

Healthcare (Basel)
Niles C, Yoshida K, Vickers K, Anderson J, El-Lahib Y, Hamdy R, Al Awamry N.   +6 more
europepmc   +1 more source

A general model for analysis of linear and hyperbolic enzyme inhibition mechanisms

FEBS Open Bio, EarlyView.
We developed a general enzyme kinetic model that integrates these six basic inhibition mechanism onto a single one. From this model, we deduced a general enzyme kinetic equation that through modulation of simple parameters, γ (the relative inhibitor affinity for two binding sites) and β (the reactivity of the enzyme–substrate–inhibitor complex), is ...
Rafael S. Chagas, Sandro R. Marana
wiley   +1 more source

Black Infant Deaths Point to Flaw in U.S. Health Care System

, 2014
Vanessa Lopez‐Littleton
openalex   +1 more source

Development and evaluation of a systems-based point-of-care ultrasound curriculum for a master of science in athletic training program [PDF]

Joshua I. Johnson, Christopher M. Ludwig, Russell T. Baker   +2 more
openalex   +1 more source