Results 251 to 260 of about 3,351,259 (336)

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Meeting the challenges of electronic health record (EHR) optimization. [PDF]

NPJ Digit Med
Makhni S, Cerrato P, Rico J, Niazi S, O'Horo J, Peters S, Shah V, Halamka J.   +7 more
europepmc   +1 more source

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

How to design decision-support tools for primary healthcare using a human-centred design approach: the processes and experience of PHISICC in three Sub-Saharan countries. [PDF]

BMJ Glob Health
Rodriguez Franco D, Co-creation groups, Auer C, Zuske MK, Oyo-Ita A, Muloliwa A, Yapi RB, Berté S, Samba M, Garba AB, Njepuome AN, Ekpenyong N, Matsinhe G, Brown D, Krause LK, Sacarlal J, Bosch-Capblanch X.   +16 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

How can ethnobiology and ethnomedicine foster more applied and concrete solutions to safeguard medicinal systems of indigenous, Afro-descendant and local communities? [PDF]

J Ethnobiol Ethnomed
Odonne G, Zank S.
europepmc   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Innovative hematological strategies to combat maternal and child mortality in Africa: focus on anemia and sickle cell disease. [PDF]

Ann Med Surg (Lond)
Obeagu EI.
europepmc   +1 more source

Identification of design features to enhance utilization and acceptance of systems for Internet-based decision support at the point of care.

, 1998
C S Gadd, P Baskaran, David F. Lobach
openalex   +1 more source

Integrating advanced Microfluidic lateral flow systems with a finger-prick blood collection cartridge to create an all-in-one platform for point-of-care diagnostics

Fatemeh Haghayegh, Elnaz Haghani, Alireza Norouzi Azad, Hamidreza Akbari Ghavamabadi, Sunil Aggarwal, Ryan Orszulik, Sergey N. Krylov, Ashissh Raichura, Razieh Salahandish   +8 more
openalex   +1 more source