Results 111 to 120 of about 2,450,308 (424)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

The cost-effectiveness of upfront point-of-care testing in the emergency department: a secondary analysis of a randomised, controlled trial

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine, 2019
Background Time-saving is constantly sought after in the Emergency Department (ED), and Point-of-Care (POC) testing has been shown to be an effective time-saving intervention.
Lara Nicole Goldstein   +2 more
doaj   +1 more source

Comparison of different goodness-of-fit tests [PDF]

open access: yesarXiv, 2002
Various distribution free goodness-of-fit test procedures have been extracted from literature. We present two new binning free tests, the univariate three-region-test and the multivariate energy test. The power of the selected tests with respect to different slowly varying distortions of experimental distributions are investigated. None of the tests is
arxiv  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Development and Implementation of an Influenza Point-Of-Care Testing Service in a Chain Community Pharmacy Setting

open access: yesPharmacy, 2020
Point-of-care testing is becoming increasingly commonplace in community pharmacy settings. These tests are often used in the management of chronic disease, such as blood sugar, hemoglobin A1c and lipid levels, but can also be used for acute conditions ...
Rachel Hardin   +6 more
doaj   +1 more source

Multiple Monte Carlo Testing with Applications in Spatial Point Processes [PDF]

open access: yesarXiv, 2015
The rank envelope test (Myllym\"aki et al., Global envelope tests for spatial processes, arXiv:1307.0239 [stat.ME]) is proposed as a solution to multiple testing problem for Monte Carlo tests. Three different situations are recognized: 1) a few univariate Monte Carlo tests, 2) a Monte Carlo test with a function as the test statistic, 3) several Monte ...
arxiv  

Advancing prevention of sexually transmitted infections through point-of-care testing : target product profiles and landscape analysis [PDF]

open access: yes, 2017
Objectives: Advancing the field of point-of-care testing (POCT) for STIs can rapidly and substantially improve STI control and prevention by providing targeted, essential STI services (case detection and screening).
Blondeel, Karel   +5 more
core   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

open access: yesMolecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever   +1 more
wiley   +1 more source

'Point-of-care' D-dimer testing [PDF]

open access: yesJournal of Medical Biochemistry, 2010
D-dimer testing is efficient in the exclusion of venous thromboembolism (VTE). D-dimer laborator y assays are predominantly performed in centralised laboratories in intra-hospital settings although most patients with suspected VTE are presented in ...
Antović Jovan P.
doaj  

A Logical Approach to Generating Test Plans [PDF]

open access: yesarXiv, 2016
During the execution of a test plan, a test manager may decide to drop a test case if its result can be inferred from already executed test cases. We show that it is possible to automatically generate a test plan to exploit the potential to justifiably drop a test case and thus reduce the number of test cases.
arxiv  

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