Results 241 to 250 of about 2,450,308 (424)

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Machine learning in point-of-care testing: innovations, challenges, and opportunities. [PDF]

Nat Commun
Han GR, Goncharov A, Eryilmaz M, Ye S, Palanisamy B, Ghosh R, Lisi F, Rogers E, Guzman D, Yigci D, Tasoglu S, Di Carlo D, Goda K, McKendry RA, Ozcan A.   +14 more
europepmc   +1 more source

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Point-of-care testing of hyponatremia and hypernatremia levels: An optoplasmonic biosensing approach. [PDF]

PLoS One
Hoque AMT, Islam A, Haider F, Aoni RA, Ahmed R.   +4 more
europepmc   +1 more source

Comparison of a Fully Automated Immunoassay with a Point-of-Care Testing Method for B-Type Natriuretic Peptide [PDF]

, 2005
Concetta Prontera, Simona Storti, Michele Emdin, Claudio Passino, Luc Zyw, Gian Carlo Zucchelli, Aldo Clerico   +6 more
openalex   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Regulation and governance for the implementation and management of point-of-care testing in Australia: a scoping review. [PDF]

BMC Public Health
Prestedge J, Kaufman C, Williamson DA.
europepmc   +1 more source

Does Point-Of-Care Testing Save Money or Cost More? [PDF]

, 2005
Glen L. Hortin
openalex   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Rapid microbiological respiratory point-of-care testing: a qualitative study with primary care clinicians. [PDF]

Br J Gen Pract
Clarke R, Brown E, Hay AD, Mitchell PM, Ridd MJ, Zhu L, Yardley L.   +6 more
europepmc   +1 more source