Results 251 to 260 of about 2,450,308 (424)

Stellungnahme der Arbeitsgemeinschaft “Point-of-Care Testing” der DGKL zum Thema Vernetzung von POCT-Geräten im Krankenhaus mit Zentrallabor Comments by the working group “point-of-care-testing” of the DGKL on the subject of linking POCT instruments in hospitals with a central laboratory [PDF]

, 2005
Peter B. Luppa, Norbert Gässler, Rainer Haeckel, Petra Hänecke, Gerd Häfner, Theodor Koschinsky, H. Schlebusch, Hans Günter Wahl, Heiko Ziervogel   +8 more
openalex   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

Molecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini, Giada Mele, Marika Attili, Maria Rita Assenza, Fulvio Saccoccia, Francesca Sardina, Cinzia Rinaldo, Roberto Massari, Nicola Tirelli, Alfredo Pontecorvi, Fabiola Moretti   +10 more
wiley   +1 more source

Limitations of point-of-care testing for low SARS CoV-2 loads: Insights for future pandemics. [PDF]

Afr J Prim Health Care Fam Med
Rukasha I.
europepmc   +1 more source

Point of Care Testing : Now and Future(<Special Issue>Micro-Machine Technology and Point of Care Testing (POCT))

, 2002
T. Ishigami
openalex   +2 more sources

Point-of-care C-reactive protein testing in febrile children in general practice [PDF]

, 2006
Miriam Monteny, Marjolein H. ten Brinke, J. van Brakel, Yolanda B. de Rijke, Marjolein Y. Berger   +4 more
openalex   +1 more source

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Evaluating the effect of computer-based education on pharmacist behaviour regarding point-of-care testing. [PDF]

Explor Res Clin Soc Pharm
Hussein R, Nakhla N, Shim KM, Goh J, Killeen R, Grindrod K.   +5 more
europepmc   +1 more source

Microchip Electrophoresis System "MCE-2010" : μTAS Technology for POCT(<Special Issue>Micro-Machine Technology and Point of Care Testing (POCT))

, 2002
H. Nakanishi
openalex   +2 more sources

Point-of-Care Testing and Equity [PDF]

Archives of Pathology & Laboratory Medicine, 2020
openaire   +3 more sources

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source