Results 291 to 300 of about 2,450,308 (424)

Improving management of patients with acute cough by C-reactive protein point of care testing and communication training (IMPAC3T): study protocol of a cluster randomised controlled trial [PDF]

, 2007
Jochen Cals, Rogier Hopstaken, Christopher Butler, Kerenza Hood, Johan L. Severens, Geert‐Jan Dinant   +5 more
openalex   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Point-of-Care Testing (POCT) for Blood Gas and Electrolyte Analysis in Out-of-Hospital Cardiac Arrests' Management; a Cross-sectional Study. [PDF]

Arch Acad Emerg Med
Tienpratarn W, Yuksen C, Chukaew L, Jenpanitpong C, Triganjananun C, Seesuklom S.   +5 more
europepmc   +1 more source

1083: Impact of Risk Factors on the Performance of a Point-of-Care Bladder Cancer Test [PDF]

, 2007
Yair Lotan
openalex   +1 more source

Revealing protein structures: crystallization of protein‐ligand complexes – co‐crystallization and crystal soaking

FEBS Open Bio, Volume 15, Issue 4, Page 542-550, April 2025.
Co‐crystallization crystallizes a protein with its ligand, resulting in protein–ligand complex crystals. In contrast, soaking introduces a ligand into preformed protein crystals, allowing it to bind. Both methods produce crystals for X‐ray diffraction, which generates diffraction patterns that are analyzed to determine the three‐dimensional structure ...
Barbora Kaščáková, Anna Koutská, Michaela Burdová, Petra Havlíčková, Ivana Kutá Smatanová   +4 more
wiley   +1 more source

The feasibility of point-of-care testing for initial urinary liver fatty acid-binding protein to estimate severity in severe heatstroke. [PDF]

Sci Rep
Yokobori S, Shimazaki J, Kaneko H, Asai H, Kanda J, Takauji S, Sato E, Ichibayashi R, Fujita M, Shiraishi S, Shimizu K, Yokota H.   +11 more
europepmc   +1 more source

Expression and purification of E140 protein antigen fragments of Plasmodium vivax and Plasmodium berghei for serological assays

FEBS Open Bio, Volume 15, Issue 5, Page 690-698, May 2025.
We provide a step‐by‐step guide for producing E140 antigen fragments from Plasmodium berghei (Pb1) and Plasmodium vivax (Pv1). Pb1/Pv1 are expressed in E. coli, solubilized by freeze–thawing, refolded by slow dilution, purified by affinity chromatography (IMAC), then concentrated and subjected to quality control.
Rodolfo Ferreira Marques, Edit Ábrahám, Hiromi Muramatsu, Daniel Youssef Bargieri, Norbert Pardi, Zoltán Lipinszki   +5 more
wiley   +1 more source

An Injection Molded SlipChip with Self-Sampling for Integrated Point-of-Care Testing of Human Papilloma Virus. [PDF]

Adv Sci (Weinh)
Zhang J, Dong Z, Xu L, Han X, Sheng Z, Chen W, Zheng J, Lai D, Shen F.   +8 more
europepmc   +1 more source

Synergistic antibacterial activity of baicalin in combination with oxacillin sodium against methicillin‐resistant Staphylococcus aureus

FEBS Open Bio, Volume 15, Issue 4, Page 608-621, April 2025.
The bacterial cell membrane and cell wall are the primary targets of baicalin. Baicalin increases the permeability of bacterial membranes, allowing oxacillin sodium to easily penetrate the cells and effectively exert its antimicrobial activity. Methicillin‐resistant Staphylococcus aureus (MRSA) poses a challenge for clinical treatment and combining ...
Xin Meng, Mengna Kang, Zhiyun Yu, Changyou Li, Yang Chen, Taicheng Jin, Kai Wang, Haiyong Guo   +7 more
wiley   +1 more source