Results 71 to 80 of about 2,450,308 (424)

Role of Point-of-Care Testing in Reducing Time to Treatment Decision-Making in Urgency Patients: A Randomized Controlled Trial [PDF]

open access: yes, 2020
Introduction: Shortening emergency department (ED) visit time can reduce ED crowding, morbidity and mortality, and improve patient satisfaction. Point-of-care testing (POCT) has the potential to decrease laboratory turnaround time, possibly leading to ...
Chaisirin, Wansiri   +10 more
core  

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Point-of-Care Testing – Biosensor for Norepinephrine Determination [PDF]

open access: yes, 2020
An useful electrochemical sensing approach was developed for norepinephrine (NE) detection based on semiconducting polymer (9-nonyl-2,7-di(selenophen-2-yl)-9H-carbazole) and laccase modified platinum electrode (Pt).
Baluta, Sylwia   +3 more
core   +5 more sources

Point-of-Care Testing for Sexually Transmitted Infections: A Review of Recent Developments.

open access: yesArchives of Pathology & Laboratory Medicine, 2020
CONTEXT.— Sexually transmitted infections (STIs) are among the most common communicable diseases globally and are associated with significant morbidity and mortality worldwide.
P. Adamson, M. Loeffelholz, J. Klausner
semanticscholar   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1055-1074, April 2025.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard   +7 more
wiley   +1 more source

Perceptions of point-of-care infectious disease testing among European medical personnel, point-of-care test kit manufacturers, and the general public

open access: yesPatient Preference and Adherence, 2013
Wendy E Kaman,1 Eleni-Rosalina Andrinopoulou,2 John P Hays11Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, Rotterdam, The Netherlands; 2Department of Biostatistics, Erasmus Medical Center, Rotterdam, The ...
Kaman WE, Andrinopoulou ER, Hays JP
doaj  

Performance evaluation of all analytes on the epoc® Blood Analysis System for use in hospital surgical and intensive care units

open access: yesPractical Laboratory Medicine, 2020
Objective: To evaluate the performance of the epoc hand-held analyzer against the RAPIDPoint 500 blood gas analyzer and laboratory analyzers where applicable. Methods: Venous or arterial whole blood samples collected in balanced heparinized syringes were
Zahraa Mohammed-Ali   +7 more
doaj  

The Efficiency of Quantum Identity Testing of Multiple States [PDF]

open access: yesJ. Phys. A: Math. Theor. 41 (2008) 395309, 2008
We examine two quantum operations, the Permutation Test and the Circle Test, which test the identity of n quantum states. These operations naturally extend the well-studied Swap Test on two quantum states. We first show the optimality of the Permutation Test for any input size n as well as the optimality of the Circle Test for three input states.
arxiv   +1 more source

Cytosolic‐enhanced dark Epac‐based FRET sensors allow for intracellular cAMP detection in live cells via FLIM

open access: yesFEBS Letters, Volume 599, Issue 7, Page 1075-1085, April 2025.
We describe a novel set of Epac‐based FRET‐FLIM biosensors with improved fully cytosolic distribution, achieved without compromising the state‐of‐the‐art performance of our original designs, for detecting cAMP dynamics in real time in live cells with high precision and reliability.
Giulia Zanetti   +2 more
wiley   +1 more source

Overcoming Challenges With the Adoption of Point-of-Care Testing

open access: yesPoint of Care, 2020
Supplemental digital content is available in the text. Abstract Major technical challenges often prevent developers from producing new point-of-care technologies that deliver the required clinical performance in the intended settings of use.
Brenda Korte   +3 more
semanticscholar   +1 more source

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