Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Specialized Diagnostics are Required for the Management of an Intraparotid Facial Nerve Schwannoma.
Finsterer J.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Tips for Accurate Beath Pin Length Measurement While Using an Arthroscopic Jig to Avoid Neurovascular Injury Due to Over Penetration (Hit-Pat's Method). [PDF]
Patil HG, Pimprikar MV, Patil CK.
europepmc +1 more source
Nonspecific lower back pain in overhead athletes is multifactorial and is not solely determined by the type and intensity of the sport. [PDF]
Finsterer J.
europepmc +1 more source
Reply to Dey and Schreiber: Porous media framework of intracellular diffusion is not limited to inert molecules. [PDF]
Destrian O +4 more
europepmc +1 more source
The Effectiveness of Fu's Subcutaneous Needling for Residual Pain After Percutaneous Vertebral Augmentation in Osteoporotic Vertebral Compression Fractures: A Randomized Clinical Trial Protocol [Letter]. [PDF]
Chen LQ, Ma RJ.
europepmc +1 more source
A Rare Cause of Small Bowel Obstruction: Malignant Metastatic Sarcoma. [PDF]
Ponce A, Davis T, Jones TM.
europepmc +1 more source

