Results 91 to 100 of about 255,061 (262)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

A survey on point-of-interest recommendations leveraging heterogeneous data

Information Technology & Tourism
Abstract Tourism is an important application domain for recommender systems. In this domain, recommender systems are for example tasked with providing personalized recommendations for transportation, accommodation, points-of-interest (POIs), etc.
Zehui Wang, Wolfram Höpken, Dietmar Jannach   +2 more
openaire   +2 more sources

Dual Branch Graph Representation Learning-Based Approach for Next Point-of-Interest Recommendation

IEEE Access
Next Point-of-Interest (POI) recommendation, a sub-task of POI recommendation, focuses on predicting the next POI a user will visit, relying on the user’s sequential check-in history.
Guoning Lv, Min Gao
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

A Survey on Point-of-Interest Recommendation: Models, Architectures, and Security

IEEE Transactions on Knowledge and Data Engineering
The widespread adoption of smartphones and Location-Based Social Networks has led to a massive influx of spatio-temporal data, creating unparalleled opportunities for enhancing Point-of-Interest (POI) recommendation systems. These advanced POI systems are crucial for enriching user experiences, enabling personalized interactions, and optimizing ...
Qianru Zhang, Peng Yang 0016, Junliang Yu, Haixin Wang 0003, Xingwei He 0003, Siu-Ming Yiu, Hongzhi Yin   +6 more
openaire   +4 more sources

Optimized tourist point-of-interest recommendation through ARIMA and SVD in edge environment

Journal of Cloud Computing: Advances, Systems and Applications
In edge computing environments, accurate and timely Point of Interest (POI) recommendation is critical for enhancing tourist user experience and service efficiency.
Haibo Dong, Zhenxiang Liu, Edris Khezri
doaj   +1 more source

Hierarchical Graph Learning with Cross-Layer Information Propagation for Next Point of Interest Recommendation

Applied Sciences
With the vast quantity of GPS data that have been collected from location-based social networks, Point-of-Interest (POI) recommendation aims to predict users’ next locations by learning from their historical check-in trajectories.
Qiuhan Han, Atsushi Yoshikawa, Masayuki Yamamura   +2 more
doaj   +1 more source