Results 111 to 120 of about 4,714,518 (295)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Environmental Research Letters, 2018 The term tipping point has experienced explosive popularity across multiple disciplines over the last decade. Research on social-ecological systems (SES) has contributed to the growth and diversity of the term’s use.
Manjana Milkoreit +9 more
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Social Sciences and Humanities OpenRecent scholarship on multilingual learners (MLs) often highlights classroom marginalization and linguistic discourse, yet there is limited focus on pedagogical strategies and professional development (PD) for ML teachers.
Gift Onwubuya
doaj +1 more source
Design and development of a laminated Fresnel lens for point-focus PV systems. Phase II [PDF]
, 1982 A laminated glass-plastic lens parquet using injection molded point focus Fresnel lenses is described. The second phase of a program aimed at investigating the cost effectiveness of a glass-plastic concentrator lens assembly is reported. The first phase dealt with the development of a first generation lens design, the selection of the preferred glass ...
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Solar thermal plant impact analysis and requirements definition [PDF]
Progress on a continuing study comprising of ten tasks directed at defining impact and requirements for solar thermal power systems (SPS), 1 to 10 MWe each in capacity, installed during 1985 through year 2000 in a utility or a nonutility load in the ...
Gupta, Y. P.
core +1 more source
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Journal of Marine Science and EngineeringPursuing sustainable energy solutions has prompted researchers to focus on optimizing energy extraction from renewable sources. Control laws that optimize energy extraction require accurate modeling, often resulting in time-varying, nonlinear ...
Houssein Yassin +4 more
doaj +1 more source