Results 81 to 90 of about 4,714,518 (295)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Solution of classical stochastic one dimensional many-body systems

, 1999
We propose a simple method that allows, in one dimension, to solve exactly a wide class of classical stochastic many-body systems far from equilibrium.
A. A. Lushnikov, B. P. Lee, D. C. Mattis, F. C. Alcaraz, J. E. Santos, J. L. Cardy, K. Krebs, M. D. Grynberg, M. D. Grynberg, M. Mobilia, P.-A. Bares, P.-A. Bares, V. E. Korepin, V. R. Jones   +13 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Global Transformative Leadership in the 21st Century: A Science, Engineering, Technology Integrated and Strategic Perspective

Cadmus, 2020
The goal of this paper is to focus on the Global Leadership Challenge in the 21st Century with an integrated and strategic perspective in science, engineering and technology (SET).
Rodolfo Fiorini, Carlos Alvarez Pereira, Garry Jacobs, Donato Kiniger-Passigli, Alberto Zucconi, Nebojša Nešković, Herwig Schopper, Vojislav Mitic, Hazel Henderson, Mariana Todorova, Witold Kinsner, Luigi Cocchiarella   +11 more
doaj  

Quantum and Topological Criticalities of Lifshitz Transition in Two-Dimensional Correlated Electron Systems

, 2006
We study electron correlation effects on quantum criticalities of Lifshitz transitions at zero temperature, using the mean-field theory based on a preexisting symmetry-broken order, in two-dimensional systems.
Brandt N. B., Chu C. W., Chuang Y.-D., Egorov V. S., Egorov V. S., Hertz J. A., Hlubina R., Honerkamp C., Imada M., Kaminski A., Kimura N., Lifshitz I. M., Lorenzana J., Makarov V. I., Millis A. J., Millis A. J., Misawa T., Moreo A., Ong N. P., Pan S. H., Pfleiderer C., Sachdev S., Sandeman K. G., Struzhkin V. V., Takagi H., Uhlarz M., Wen X. G.   +26 more
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Real time dynamics from low point correlators in 2d BCFT

Journal of High Energy Physics, 2019
In this article, we demonstrate how a 3-point correlation function can capture the out-of-time-ordered features of a higher point correlation function, in the context of a conformal field theory (CFT) with a boundary, in two dimensions.
Suchetan Das, Bobby Ezhuthachan, Arnab Kundu   +2 more
doaj   +1 more source

Topological transition between competing orders in quantum spin chains

, 2018
We study quantum phase transitions between competing orders in one-dimensional spin systems. We focus on systems that can be mapped to a dual-field double sine-Gordon model as a bosonized effective field theory.
Furuya, Shunsuke C., Giamarchi, Thierry, Takayoshi, Shintaro   +2 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source