Results 91 to 100 of about 7,539,459 (382)

Preferred Point Geometry and Statistical Manifolds

The Annals of Statistics, 1993
The authors introduce a mathematical object of a preferred point geometry. Its definition and use are based on two standpoints: to be as natural and simple as possible from both the statistical and the geometric viewpoint, and to reflect in a natural way the special status of the preferred point.
Critchley, Frank, Marriott, Paul, Salmon, Mark   +2 more
openaire   +5 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

ON PRECISION ACOUSTIC WAVE CALCULATION IN A FREQUENCY DOMAIN

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2022
The accuracy of the calculation of acoustic problems formulated in the frequency domain is presented in this work. The issues of the acoustic point sources modelling were discussed and the influence of frequency as well as the impact of the geometry of ...
Tomasz Rymarczyk, Jan Sikora
doaj   +1 more source

Particle physics from the noncommutative geometry point of view [PDF]

, 1993
Recent development in noncommutative geometry generalization of gauge theory is reviewed. The mathematical apparatus is reduced to minimum in order to allow the non-mathematically oriented physicists to follow the development in the interesting field of ...
Sladkowski, Jan
core   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Accurate deformation analysis based on point position uncertainty estimation and adaptive projection point cloud comparison

Geocarto International, 2023
The accuracy of the scanning scene representation and corresponding points extraction are key factors in deformation analysis based on point cloud. Still, little is known about the influence of terrestrial laser scanner (TLS) survey properties on point ...
Wenxiao Sun, Jian Wang, Yikun Yang, Fengxiang Jin, Fuxun Sun   +4 more
doaj   +1 more source

Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to identify biomarkers of cognitive resilience and their interplay with APOE ...
Apostolos Manolopoulos, Maja Mustapic, Carlos Nogueras‐Ortiz, Francheska Delgado‐Peraza, Krishna A. Pucha, Pamela J. Yao, Joseph Blommer, Michael P. Vreones, William York, De' Larrian Knight, Stephen R. Rapp, Aladdin H. Shadyab, JoAnn E. Manson, Ramon Casanova, Robert B. Wallace, Luigi Ferrucci, Susan M. Resnick, Dimitrios Kapogiannis   +17 more
wiley   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Learning Convolutional Transforms for Lossy Point Cloud Geometry Compression [PDF]

International Conference on Information Photonics, 2019
Efficient point cloud compression is fundamental to enable the deployment of virtual and mixed reality applications, since the number of points to code can range in the order of millions. In this paper, we present a novel data-driven geometry compression
Maurice Quach, G. Valenzise, F. Dufaux
semanticscholar   +1 more source

Colchicine Concentrations and Relationship With Colchicine Efficacy and Adverse Events: Post Hoc Analysis of a Randomized Clinical Trial of Colchicine for Gout Flare Prophylaxis

Arthritis Care &Research, EarlyView.
Objective Our objective was to examine the relationship between colchicine plasma concentrations and clinical and demographic factors and to determine the relationship between colchicine concentrations and colchicine efficacy and colchicine‐specific adverse events.
Lisa K. Stamp, Anne Horne, Borislav Mihov, Jill Drake, Janine Haslett, Peter Chapman, Daniel F. B. Wright, Christopher Frampton, Nicola Dalbeth   +8 more
wiley   +1 more source