Results 191 to 200 of about 197,136 (248)

A similarity-based predictive scheduling method for dynamic electric vehicle charging load management. [PDF]

Sci Rep
Firouzjah KG, Ghasemi J.
europepmc   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

The free vibrational characteristic of PFGM beams near the post-buckling configuration under thermal loads. [PDF]

Sci Prog
Lyu Q, Zhao Y, Zeng H, Mu Y.
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

The Value of Hepatitis E Screening Sensitivity: Lookback Investigation in German Blood Donors. [PDF]

Viruses
Plümers R, Dreier J, Mandl A, Knabbe C, Vollmer T.   +4 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

Integrating climate scenarios and thermal welfare thresholds to project future heat stress risk in beef cattle. [PDF]

Int J Biometeorol
Grossi G, Vitali A, Lacetera N, Rossi C, Lacetera N.   +4 more
europepmc   +1 more source

Indices of embodied Neuroergonomic coupling: a theory and hypothesis framework for quantifying brain-body-environment dynamics in built space. [PDF]

Front Hum Neurosci
Scanlin J.
europepmc   +1 more source