Results 131 to 140 of about 196,393 (286)

Stability of dams constructed on problematic substrates

open access: yes, 2013
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Dissolution of soluble substrates such as gypsum presents a major hazard to dams in many parts of the world. This research simulates hypothesised conditions
Salih, Nihad Bahaaldeen
core  

Analysis of Rail Vehicle Axle Strength and Fatigue Crack Propagation Life

open access: yes机车电传动, 2013
Taking axle of GCY300II 12t-axle-load rail car as research object, according to locomotive axle strength standards, axle static and fatigue strength of the six different conditions with different axle load was calculated with finite element method. Based
LI Rui-xia   +3 more
doaj  

Long‐Term Neurologic Exam Findings in People Diagnosed and Treated During Acute HIV Infection

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Evaluate clinical and laboratory correlates of abnormal neurologic exam findings after acute HIV infection (AHI). Methods Participants from the RV254/SEARCH 010 cohort in Bangkok underwent standardized neurologic examinations at Weeks 0 (AHI), 12, 96, and 288 following antiretroviral therapy (ART).
Kathryn B. Holroyd   +118 more
wiley   +1 more source

A Study on the Correlation between Uniaxial Compressive Strength and Point Load Strength Index of Limestone of Imgye Area

open access: yes, 2012
Though the uniaxial compressive strength (UCS) of rock material is one of the key properties for rockmass characterization purposes, core samples for the test cannot always be obtained from the field.
Dae Hoon Kim   +5 more
core  

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch   +5 more
wiley   +1 more source

Temporal Interference Stimulation of Centromedian‐Parafascicular Complex in Disorders of Consciousness: A Pilot Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Treatment of disorders of consciousness (DoC) remains a major clinical challenge, and noninvasive, targeted modulation of deep brain structures has emerged as a promising therapeutic strategy. We aimed to evaluate the feasibility/safety and preliminary effects of thalamic temporal interference stimulation (TIS) targeting centromedian‐
Gengyao Hu   +7 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian   +6 more
wiley   +1 more source

Point Load Index Applicability to Predicting Rocks' Uniaxial Compressive and Tensile Strengths: Available Data Analysis and FEM-Based Validity Check

open access: yes
In projects that are in contact with rocks, it is very important to determine the strength parameters of the rock correctly. While there are several approaches to this, the experimental approach is the most recommended.
Akbay, Deniz
core   +1 more source

Association Between Symptomatic Knee Osteoarthritis and Target Glycemic Control in Individuals With Type 2 Diabetes

open access: yesArthritis Care &Research, EarlyView.
Objective Knee osteoarthritis (OA) commonly affects individuals with type 2 diabetes (T2DM) and is associated with increased risk of diabetes‐related complications. To better understand potential mechanisms, we examined the association between symptomatic knee OA and glycemic control in individuals with T2DM.
Lauren K. King   +10 more
wiley   +1 more source

Associations of Sleep and Shift Work With Osteoarthritis Risk

open access: yesArthritis Care &Research, EarlyView.
Objective Daily rhythms may be critical for maintaining homeostasis of joint tissues. We aimed to investigate the relationships among circadian clock disruption, sleep, and osteoarthritis (OA) risk in humans. Methods In the UK Biobank, a prospective 500,000–person cohort, we evaluated associations among sleep duration, sleeplessness/insomnia, and shift
Elizabeth L. Yanik   +5 more
wiley   +1 more source

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