Results 111 to 120 of about 72,833 (270)

Using the point load test to determine the uniaxial compressive strength of coal measure rock [PDF]

open access: yes
"Point load testing is used to determine rock strength indexes in geotechnical practice. The point load test apparatus and procedure enables economical testing of core or lump rock samples in either a field or laboratory setting.

core  

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

BONE STRENGTH OF DIFFERENT PIGS GENETIC TYPES [PDF]

open access: yes, 2010
The aim of this study was to evaluate the bone strength in different genetic types of pigs. Nowadays, in swine production it is rather common to obtain pigs with weak bones, especially on the hind legs.
Griggio, Michele
core  

Paramagnetic Rim Lesions and Choroid Plexus Volume at Diagnosis Are Associated With Cognitive Progression Independent of Relapse and MRI Activity in Early Relapsing–Remitting Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) and choroid plexus (CP) enlargement reflect smoldering inflammation in multiple sclerosis. Their role in cognitive progression remains unexplored. Eighty‐seven early relapsing–remitting MS patients were enrolled at diagnosis and followed longitudinally.
Stefano Ziccardi   +15 more
wiley   +1 more source

Determination of muscle fatigue index for strength training in patients with Duchenne dystrophy

open access: yesFisioterapia em Movimento
INTRODUCTION: Muscle weakness is the most prominent impairment in Duchenne muscular dystrophy (DMD) and often involves the loss of functional ability as well as other limitations related to daily living.
Adriano Rodrigues Oliveira   +4 more
doaj   +1 more source

Upper Cervical Cord Area as a Biomarker of Conversion to Secondary Progressive Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study assessed whether upper cervical cord area (UCCA) measured on routine brain MRI can serve as a biomarker of conversion to SPMS. Methods This is a single‐center retrospective cohort study of RRMS patients with cross‐sectional and longitudinal analyses of clinical and MRI data. Future SPMS converters were matched by age, sex,
Nabil K. El Ayoubi   +8 more
wiley   +1 more source

Investigation of the factors that effect the point load strength test by using synthetic samples

open access: yes, 2011
Nokta yükü dayanım indeksi deneyi kayaçların dayanımlarına göre sınıflandırılmasında ve tek eksenli basınç dayanımının dolaylı yönden tahmin edilmesinde kullanılan bir indeks deneydir.
Demir, Meryem
core  

Macroscopic and Microscopic Investigation on Microfractures in Blast-Conditioned Rock and the Influence of Particle Size

open access: yesApplied Sciences
In the mining industry, particle size reduction is the most energy-demanding activity. Blasting represents the first stage of comminution. Experimental and field observations have demonstrated that blasting produces two main effects on rock: (i ...
Jacopo Seccatore   +4 more
doaj   +1 more source

Integration of Serum Neurofilament Light Chain and Cortical Dysfunction Improves Diagnostic Accuracy in ALS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether integration of serum neurofilament light chain (NfL) and cortical dysfunction improves diagnostic accuracy in amyotrophic lateral sclerosis (ALS) when applied alongside the Gold Coast criteria (GCC). Methods In this prospective study, 148 participants with suspected ALS were recruited (101 ALS and 47 with ALS ...
Aicee Dawn Calma   +16 more
wiley   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand   +5 more
wiley   +1 more source

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