Results 121 to 130 of about 5,946,577 (342)

Point-of-Care Diagnostics

, 2014
Rapid tests that are low-cost and portable are the first line of defence in healthcare systems. Dipstick and lateral-flow are the two universal assay formats as they are lightweight and compact, and provide qualitative results without external instrumentation.
openaire   +2 more sources

Multi-point, multi-wavelength fluorescence monitoring of DNA separation in a lab-on-a-chip with monolithically integrated femtosecond-laser-written waveguides [PDF]

, 2009
Electrophoretic separation of fluorescently labeled DNA molecules in on-chip microfluidic channels was monitored by integrated waveguide arrays, with simultaneous spatial and wavelength resolution.
Besselink, G.A.J., Cerullo, G., Dekker, R., Dongre, C., Hoekstra, H.J.W.M., Martinez Vazquez, R., Osellame, R., Pollnau, M., Ramponi, R., Vlekkert, H.H. van den, Weeghel, R. van, Weerd, J. van   +11 more
core   +2 more sources

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

Factors determining patients' intentions to use point-of-care testing medical devices for self-monitoring: the case of international normalized ratio self-testing

Patient Preference and Adherence, 2012
Syed Ghulam Sarwar Shah,1 Julie Barnett,1 Jasna Kuljis,2 Kate Hone,2 Richard Kaczmarski31Multidisciplinary Assessment of Technology Centre for Healthcare, 2Department of Information Systems and Computing, Brunel University London, Uxbridge, Middlesex, UK;
Shah SG, Barnett J, Kuljis J, Hone K, Kaczmarski R   +4 more
doaj  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Point-of-care assessment of haemostasis after cardiopulmonary bypass [PDF]

, 1999
Michael S. Avidan, Beverley J. Hunt
openalex   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

The interplay between the tumor microenvironment and tumor-derived small extracellular vesicles in cancer development and therapeutic response

Cancer Biology & Therapy
The tumor microenvironment (TME) plays an essential role in tumor cell survival by profoundly influencing their proliferation, metastasis, immune evasion, and resistance to treatment.
Xuanyu Guo, Jiajun Song, Miao Liu, Xinyi Ou, Yongcan Guo   +4 more
doaj   +1 more source

The Use of Point-of-Care Ultrasound for Arthrocentesis Among Emergency Medicine Residents

Open Access Emergency Medicine, 2021
Josie Acuna, Adrienne Yarnish, Elaine Situ-LaCasse, Richard Amini, Srikar Adhikari Department of Emergency Medicine, University of Arizona, Tucson, AZ, USACorrespondence: Josie AcunaDepartment of Emergency Medicine, The University of Arizona Medical ...
Acuna J, Yarnish A, Situ-LaCasse E, Amini R, Adhikari S   +4 more
doaj  

Point of care testing improves process but not outcome in patients in A and E [PDF]

, 1998

openalex   +1 more source