Results 131 to 140 of about 5,946,577 (342)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Choosing wisely: Improving decision-making for deployment of diagnostics in primary care settings

Journal of Family Medicine and Primary Care
Background: Despite the availability of WHO and ICMR’s list of essential diagnostics, there is limited guidance to primary care providers on choosing and deploying the most appropriate diagnostics. Objectives: The study aimed to identify diagnostic tests
Varsha Shridhar, Vasudha Kannan, Ramakrishna Prasad, Pavitra Mohan   +3 more
doaj   +1 more source

Point-of-care ultrasonography for anesthesiologists☆

Colombian Journal of Anesthesiology, 2015
La ecografia hecha por el clinico (POCUS por su sigla en ingles: point-of-care ultrasound) se realiza e interpreta al lado de la cama del paciente. De esa forma se obtienen hallazgos en tiempo real, es posible establecer la correlacion clinica con los signos y sintomas, y ademas se pueden repetir las imagenes dinamicas en caso de cambios en la ...
openaire   +2 more sources

Point-of-Care Testing: Teamwork and Collaboration Initiate Health Care Change [PDF]

, 1997
Vicki Kendrick, Mary Cavin, Kathryn Vorster   +2 more
openalex   +1 more source

Image to Fit the Clinical Picture: Point-of-care Ultrasound Assessment of Ebstein’s Anomaly in Peru [PDF]

, 2020
Ebstein’s anomaly is a congenital heart defect that when left untreated can lead to unique physical exam and ultrasound findings. This case describes a patient who presented with dyspnea and was found to have cyanosis, clubbing, and dilation of right ...
Dreyfuss, Andrea, Inga, Roberto, Rider, Ashley C.   +2 more
core  

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Point-of-Care Testing of Triglycerides: Evaluation of the Accutrend Triglycerides System [PDF]

, 2000
Claus Luley, Gunnar Ronquist, W Reuter, Valerie Paal, Hans-Detlev Gottschling, Sabine Westphal, George L. King, Stephan J. L. Bakker, Robert J. Heine, Andrew Hattemer   +9 more
openalex   +1 more source

Point-of-care tests for STIs: the way forward. [PDF]

, 2017
Askew, Ian, Ballard, Ronald, Holmes, King, Kiarie, James, Mabey, David, Peeling, Rosanna W, Toskin, Igor   +6 more
core   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Assessment of five portable blood glucose meters, a point-of-care analyzer, and color test strips for measuring blood glucose concentration in dogs [PDF]

, 2000
Leah A. Cohn, Dudley L. McCaw, Deborah Tate, J. M. Johnson   +3 more
openalex   +1 more source