Results 71 to 80 of about 5,946,577 (342)

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Aspects of Point-of-Care Diagnostics for Personalized Health Wellness

International Journal of Nanomedicine, 2021
Sandeep Kumar,1 Monika Nehra,1 Sakina Khurana,1 Neeraj Dilbaghi,1 Vanish Kumar,2 Ajeet Kaushik,3 Ki-Hyun Kim4 1Department of Bio and Nano Technology, Guru Jambheshwar University of Science and Technology, Hisar, Haryana 125001, India; 2National Agri-Food
Kumar S, Nehra M, Khurana S, Dilbaghi N, Kumar V, Kaushik A, Kim KH   +6 more
doaj  

Point-of-Care Ultrasound for Critical Care

MedEdPORTAL, 2013
Abstract This is a resource for bedside ultrasound training. It outlines a two-day workshop designed to teach fundamental bedside ultrasound skills to critical care providers. Each day consists of two didactic sessions and four practical (hands-on) stations. Day One. Didactics: The Basics of Ultrasound and Vascular Access, Thoracic Ultrasound. Hands-on
Dana Sajed, Richard Fagley, Robert Zierler, Matthew Hallman, Shailaja Hayden, Amy Morris, Sun-Jung Lim, David R. Park, Patricia Kritek   +8 more
openaire   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

FEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. [PDF]

, 2018
BACKGROUND: Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown.
Adamson, Philip D., Berry, Colin, Boon, Nicholas A., Boylan, Heather, Brown, Ammani, Connolly, Eugene, Dweck, Marc R., Farrell, Lesley, Flather, Marcus, Forbes, John, Frood, Alison, Glover, Caroline, Hunter, Amanda, Johnstone, Janet, Lanaghan, Kirsten, Lewis, Stephanie, MacLean, Scott, Mangion, Kenneth, McGlynn, Deborah, McGregor, Lorraine, McLennan, Evonne, Mills, Nicholas L., Mordi, Ify, Murdoch, Laura, Newby, David E., Norrie, John, Paterson, Victoria, Roditi, Giles, Shah, Anoop S.V., Steedman, Tracey, Teenan, Marion, Teyhan, Fiona, The SCOT-HEART Investigators,, Timmis, Adam D., Tzemos, Nikolaos, van Beek, Edwin J.R., Williams, Michelle C., Woodward, Rosie   +37 more
core   +6 more sources

Intron‐oriented HTLV‐1 integration in an adult T‐cell leukemia/lymphoma cell line sustains expression of intact ift81 mRNA

FEBS Letters, EarlyView.
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi, Yuka Hirosawa, Yusaku Sagisaka, Minami Hama, Satoshi Takeda, Jun A. Komano   +5 more
wiley   +1 more source

Beliefs and Attitudes of Medical Students from Public and Private Universities in Malaysia towards Individuals with HIV/AIDS [PDF]

, 2013
We describe the findings from a survey assessing the beliefs regarding testing, confidentiality, disclosure, and environment of care and attitudes towards care of people with HIV/AIDS (PLHWA), in 1020, 4th and 5th year medical students, from public and ...
Choy, K. K., Khan, S. A., Rene, T. J.
core   +3 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

FEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu, Huseyn Babayev, Ismail Ogulur, Sena Ardicli, Yagiz Pat, Duygu Yazici, Bingjie Zhao, Lihong Chang, Xiaoqing Liu, Paolo D'Avino, Manru Li, Ceren Biçer, Fatma Hacer Kurtoğlu Babayev, Raja Dhir, Kari C. Nadeau, Marie‐Charlotte Brüggen, Mubeccel Akdis, Cezmi A. Akdis   +17 more
wiley   +1 more source

Schwartz Rounds: Supporting the emotional wellbeing of our future healthcare workforce

Future Healthcare Journal
There is a pressing need to increase the availability of emotional support to healthcare professionals in training and those in early career, in particular junior doctors. Schwartz Rounds provide a space for staff and students to reflect on the emotional
Laura Golding
doaj   +1 more source