Results 141 to 150 of about 2,814,147 (345)

A spatiotemporal selective bioinspired hybrid system engineered for preventing post-thrombolysis recurrence by inhibiting the ferroptosis pathway and reprogramming macrophages

Acta Pharmaceutica Sinica B
Cardiovascular diseases induced by arterial thrombosis, such as myocardial infarction and ischemic stroke, have gradually emerged as critical threats to human life and health.
Tianjiao Hao, Bin Gao, Yuanyuan Zhou, Chang Liu, Chuanjiang Ran, Binghua Chang, Wei You, Qiyue Wang, Jun Ye, Yan Shen   +9 more
doaj   +1 more source

From Professional Business Partner to Strategic Talent Leader : What’s Next for Human Resource Management [PDF]

, 2002
The HR profession is at a critical inflection point. It can evolve into a true decision science of talent, and aspire to the level of influence of disciplines such as Finance and Marketing, or it can continue the traditional focus on support services and
Boudreau, John W., Ramstad, Peter M.
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Early recognition and mobilization of resources in managing amniotic fluid embolism for a high-risk obstetric patient: A case report

Case Reports in Women's Health
A 33-year-old woman, gravida 3 para 2, at 39 weeks of gestation, undergoing induction of labor, had a seizure. She was transferred to the operating room and underwent a cesarean delivery for non-reassuring fetal status.
R. Zbeidy, Anh P. Le, Sarah M. Jacobs, Alexander W.M. Hall, P. Toledo   +4 more
doaj   +1 more source

A Whole-Class Support Model for Early Literacy: The Anna Plan [PDF]

, 2004
The Anna Plan is a unique delivery model for enhancing schoolwide literacy instruction in the primary grades. Based on the principles of Reading Recovery and Four Blocks literacy instruction, it provides supplementary reading instruction through the ...
Henk, Bill, Hubbs, Karen G, Mallette, Marla H, Miles, Pamela A, Stegle, Kathy W   +4 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Taking the Next Step in Obstetric Critical Care: Cardiac and Lung POCUS Training for Obstetric Residents

POCUS Journal
Background: The importance of cardiopulmonary point of care ultrasound (POCUS) for the assessment of the acute obstetric patient is increasingly recognized. Obstetricians are well-versed in ultrasound and may be able to perform POCUS with brief training.
Celia Muoser, Avish Arora, Jay Im, Diana Wolfe   +3 more
doaj   +1 more source

Strategies for integrating primary health services in low- and middle-income countries at the point of delivery.

Cochrane Database of Systematic Reviews, 2011
L. Dudley, P. Garner
semanticscholar   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

Molecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor, Julio Celis, Ulrik Ringborg   +2 more
wiley   +1 more source

Checkpoint blockade and the stem‐like T cell trade‐off

Molecular Oncology, EarlyView.
Stem‐like T cells are key to the success of programmed cell death protein 1 (PD1) blockade, as they sustain long‐term anti‐tumor response by continuously generating effector CD8+ T cells. However, how these cells are maintained in cancer is not fully understood. Hor et al.
Julie M. Mazet, Johanna A. Joyce
wiley   +1 more source