Results 161 to 170 of about 3,696,026 (267)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

PENURUNAN NYERI DISMENORHOEA MENGGUNAKAN TITIK AKUPUNTUR GUANYUAN (REN 4), GUILAI (ST 29) DAN SANYINJIAO (SP 6) PADA MAHASISWI POLTEKKES SURAKARTA

open access: yes, 2015
: Dysmenorrhea, Acupoints. The purpose of this study was to determine the effectiveness ofacupuncture therapy at the point Guanyuan (Ren 4), Guilai (St 29) and Sanyinjiao (Sp 6) to painpolytechnic student dismenorrhoe in Surakarta. Design This study uses
Sumanto, Sumanto
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Interest rate, debt, distribution and capital accumulation in a post-Kaleckian model [PDF]

open access: yes
The introduction of monetary variables into post-Keynesian models of distribution and growth is an ongoing process. Lavoie (1995) has proposed a Kaleckian ?Minsky-Steindl-model? of distribution and growth, incorporating the effects debt and debt services
Hein, Eckhard
core  

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