Results 121 to 130 of about 173,968,237 (260)

Eagle Point Notice of Adopted Amendment (2006-07-31)

open access: yes, 2006
6 pp. Adopted 2006-07-31.
Eagle Point (Or.)
core  

Eagle Point Notice of Adopted Amendment (2006-07-21)

open access: yes, 2006
23 pp. Adopted 2006-07-21.
Eagle Point (Or.)
core   +1 more source

Bone metastasis: orthopedic point of view

open access: yesArchivo Médico de Camagüey, 2019
Background: cancer is a common cause of morbidity-mortality affecting many people internationally and nationally. One way of presentation is bone metastases.
Alejandro Álvarez López   +2 more
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Eagle Point Notice of Adopted Amendment (2009-01-28)

open access: yes, 2009
32 pp. Adopted 2009-01-28.
Eagle Point (Or.)
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Myrtle Point Notice of Adopted Amendment (2009-04-10)

open access: yes, 2009
6 pp. Adopted 2009-04-10.
Myrtle Point (Or.)
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Central Point Notice of Adopted Amendment (2007-02-15)

open access: yes, 2007
21 pp. Adopted 2007-02-15. Department of Land Conservation and Development Notice of Adopted AmendmentTHE AMENDEMNT IS TO UPDATE TELECOMMUNICATION ANTENNA LOCATION STANDARDS AND PROCEDURES PARTICULARLY THE USE OF BUILDING WALL AND ROOF-MOUNTED ...
Central Point (Or.)
core  

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