Results 61 to 70 of about 9,987,835 (286)

Point prevalence surveys of antimicrobial use among eight neonatal intensive care units in India: 2016

International Journal of Infectious Diseases, 2018
Background: Information about antimicrobial use is scarce and poorly understood among neonatal intensive care units (NICUs) in India. In this study, we describe antimicrobial use in eight NICUs using four point prevalence surveys (PPSs). Methods: As part
Sumanth Gandra, Gerardo Alvarez-Uria, Srinivas Murki, Sanjeev K. Singh, Ravishankar Kanithi, Dasaratha R. Jinka, Ashok K. Chikkappa, Sreeram Subramanian, Anita Sharma, Dhanya Dharmapalan, Hemasree Kandraju, Anil Kumar Vasudevan, Onkaraiah Tunga, Akhila Akula, Yingfen Hsia, Mike Sharland, Ramanan Laxminarayan   +16 more
doaj   +1 more source

Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids

Pediatric Blood &Cancer, EarlyView.
ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz, Se Whee Sammy Park, Aironas Los, Ernest Liu, Nona Struyf, Tom Erkers, Sören Lehmann, Jan J. Molenaar, Jakob Stenman, Olli Kallioniemi, Päivi Östling, Brinton Seashore‐Ludlow, Kasper Karlsson   +12 more
wiley   +1 more source

First national point prevalence survey of healthcare-associated infections and antimicrobial use in acute care hospitals in the Republic of Moldova

One Health & Risk Management, 2021
Introduction. Healthcare-associated infections (HAIs) present a major public health problem with an impact on morbidity, mortality and quality of life. On overage, up to 7% of patients in high-income countries and 10% in middle and low-income countries ...
Ecaterina BUSUIOC, Natalia CATERINCIUC
doaj   +2 more sources

Multi-centre point-prevalence survey of hospital-acquired infections in Ghana [PDF]

Journal of Hospital Infection, 2019
There is a paucity of data describing hospital-acquired infections (HAIs) in Africa.To describe the prevalence and distribution of HAIs in acute care hospitals in Ghana.Between September and December 2016, point-prevalence surveys were conducted in participating hospitals using protocols of the European Centre for Disease Prevention and Control ...
Labi, A-K, Obeng-Nkrumah, N., Owusu, E., Bjerrum, S., Bediako-Bowan, A., Sunkwa-Mills, G., Akufo, C., Fenny, A. P., Opintan, J. A., Enweronu-Laryea, C., Debrah, S., Damale, N., Bannerman, C., Newman, M. J.   +13 more
openaire   +4 more sources

Social Functioning Within the First Years After Pediatric Brain Tumor Diagnosis and the Relationship With Family Psychosocial Risk

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of pediatric brain tumors (PBTs) can experience long‐term social difficulties, impacting quality of life. Beyond medical and environmental factors, family psychosocial risk may play a role in social outcomes by shaping the caregiving environment and may provide intervention options.
Renske H. Houben, Marisa H. Huisman, Martha A. Grootenhuis, Femke K. Aarsen, Marita Partanen   +4 more
wiley   +1 more source

Identifying opportunities for antimicrobial stewardship through a point prevalence survey in an Indian tertiary-care teaching hospital

Journal of Global Antimicrobial Resistance, 2020
Objectives: Unregulated and inappropriate use of antimicrobial agents has been a major driver of antimicrobial resistance with a dangerous impact on health issues in developing nations.
Zabiuddin Ahad Mohammed, Chiranjay Mukhopadhyay, Muralidhar Varma, Vandana Kalwaje Eshwara   +3 more
doaj   +1 more source

Implementation of a multidisciplinary antimicrobial stewardship programme in a Philippine tertiary care hospital: an evaluation by repeated point prevalence surveys

Journal of Global Antimicrobial Resistance, 2021
: Objectives: Optimising antimicrobial prescribing in hospitals through antimicrobial stewardship (AMS) is essential in addressing the global threat of antimicrobial resistance.
Gina de Guzman Betito, Ines Pauwels, Ann Versporten, Herman Goossens, Mari Rose De Los Reyes, Maria Tarcela Gler   +5 more
doaj   +1 more source

Retrospective Analysis of Donor Lymphocyte Infusions in Pediatric Patients With Mixed Chimerism After Hematopoietic Stem Cell Transplantation

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk, Sebastian Michaelis, Michaela Döring, Thomas Eichholz, Ursula Holzer, Martin Ebinger, Tim Flaadt, Rupert Handgretinger, Peter Lang, Jan Frederic Weller, Markus Mezger   +10 more
wiley   +1 more source

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

A point‐prevalence survey of alcohol‐related presentations to Australasian emergency departments [PDF]

Australian and New Zealand Journal of Public Health, 2018
We report the results from our second point‐prevalence survey of alcohol harm in Australasian emergency departments (EDs). This was conducted as part of the Australasian College for Emergency Medicine (ACEM) Alcohol Harm in EDs Project.1 The project's aim was to quantify the amount of alcohol harm presenting to Australasian EDs and to raise awareness ...
Egerton-Warburton, Diana, Gosbell, Andrew, Richardson, Drew, Wadsworth, Angela, Fatovich, Daniel M   +4 more
openaire   +4 more sources