Results 101 to 110 of about 8,099,068 (351)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Modelling with measures: Approximation of a mass-emitting object by a point source

Mathematical Biosciences and Engineering, 2014
We consider a linear diffusion equation on $\Omega:=\mathbb{R}^2\setminus\overline{\Omega_\mathcal{o}}$, where $\Omega_\mathcal{o}$ is a bounded domain. The time-dependent flux on the boundary $\Gamma:=∂\Omega_\mathcal{o}$ is prescribed.
Joep H.M. Evers, Sander C. Hille, Adrian Muntean   +2 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Improving Evidence‐Based Surveillance System: Foodborne Disease Outbreak in Oyibi

Health Science Reports
Background Foodborne illness and foodborne injury can be severe and fatal and have a negative impact on human health over the long‐term period. On January 20, 2023, an unknown number of people had purchased and consumed “waakye or rice” with salad, stew,
Esther Priscilla Biamah Danquah, Kwame Adu Okyere Boadu, Jeffrey Kojo Arhin, Martha Nabila, Akua Addy, Shadrack Darko, Bright Osei   +6 more
doaj   +1 more source

The IceCube Neutrino Observatory I: Point Source Searches

, 2011
Searches for point sources of astrophysical neutrinos and related measurements: Searches for steady and time-variable sources; Follow-up programs; AGNs; GRBs; Moon shadow; Submitted papers to the 32nd International Cosmic Ray Conference, Beijing 2011 ...
The IceCube Collaboration
core  

Point source identification in non-linear advection-diffusion-reaction systems

, 2013
We consider a problem of identification of point sources in time dependent advection-diffusion systems with a non-linear reaction term. The linear counterpart of the problem in question can be reduced to solving a system of non-linear algebraic equations
Mamonov, Alexander V., Tsai, Yen-Hsi Richard   +1 more
core   +1 more source

Evaluation of Riparian Buffer for the Reduction Efficiency of Non-point Sources Using HSPF Model [PDF]

, 2019
Sihyeon Lee, Jae Moon Kim, Hyun Suk Shin, Soonchul Kwon   +3 more
openalex   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Optimizing Nitrogen Fertilizer Application for Synergistic Enhancement of Economic and Ecological Benefits in Rice–Crab Co-Culture Systems

Agronomy
The rice–crab co-culture (RC) system is a multidimensional integrated farming model with significant potential for balancing ecological and economic benefits in paddy fields.
Yang Xu, Hao Li, Hongyuan Wang, Xinzhong Du, Muhammad Amjad Bashir, Xiushuang Zhang, Wentao Sun, Miaoying An, Hongbin Liu   +8 more
doaj   +1 more source