Results 131 to 140 of about 8,099,068 (351)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Agricultural Non-Point Source Pollution in China: Causes and Mitigation Measures [PDF]

, 2012
Bo Sun, Linxiu Zhang, Linzhang Yang, Fusuo Zhang, David Norse, Zhaoliang Zhu   +5 more
openalex   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Theoretical aspects of solid and gaseous substances spreading from sources of exhalations [PDF]

Acta Montanistica Slovaca, 2000
The contribution is focused to the determination of the point of exhalation maximal concentration in the surroundings of pollution source in ground-close air layer for gases and solid particles, which of diameter does not exceed 0,1 µm.
Geldová Erika, Bobro Milan, Slanèo Pavel, Hanèu¾ák Jozef   +3 more
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Algorithm for Acoustic Wavefield in Space-Wavenumber Domain of Vertically Heterogeneous Media Using NUFFT

Mathematics
Balancing efficiency and accuracy is often challenging in the numerical solution of three-dimensional (3D) point source acoustic wave equations for layered media. To overcome this, an efficient solution method in the spatial-wavenumber domain is proposed,
Ying Zhang, Shikun Dai
doaj   +1 more source

POINT-TO-POINT FUNCTIONAL CONNECTIVITY DURING INTERCRITICAL AND SEIZURE ACTIVITIES THROUGH A SPATIAL DISCRIMINATION APPROACH TO INTRACRANIAL SOURCE GENERATORS [PDF]

, 2023
Julia Makarova, Rafael Toledano, Lidia Blazquez Llorca, Erika Herráez-Sanchez, António Gil‐Nagel, Javier DeFelipe, Óscar Herreras   +6 more
openalex   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Three-dimensional point-source localization method based on position-sensitive neutron detectors

He jishu
BackgroundThe use of neutron-based methods to locate radioactive sources within sealed containers holds great practical significance.PurposeThis study aims to locate an AmLi source within the detection space of four position-sensitive neutron detectors ...
LIANG Qinglei, LI Jinghuai, LIU Guorong, WANG Bin, ZHOU Hao, TIAN Yuan   +5 more
doaj   +1 more source

Modeling of soil moisture movement and wetting behavior under point-source trickle irrigation. [PDF]

Sci Rep, 2023
Vishwakarma DK, Kumar R, Abed SA, Al-Ansari N, Kumar A, Kushwaha NL, Yadav D, Kumawat A, Kuriqi A, Alataway A, Dewidar AZ, Mattar MA.   +11 more
europepmc   +1 more source