Results 151 to 160 of about 8,099,068 (351)

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Significance of source points.

open access: yesKampo Medicine, 1986
著者は古典に基づいて原穴の意義を探究し, 次の知見を得た。「腎を介して四関に蓄えられた五臓の精気は各々の原穴から湧出し, その反応を体表にあらわす。また, 四関は外界の精気を感受し, この周期性に合わせて五臓の精気を原穴から各々の経脈に流出させる」。
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Single-blind validation of space-based point-source detection and quantification of onshore methane emissions. [PDF]

open access: yesSci Rep, 2023
Sherwin ED   +7 more
europepmc   +1 more source

Micro-simulation as a tool to assess policy concerning non-point source pollution: the case of ammonia in Dutch agriculture [PDF]

open access: gold, 2008
Gideon Kruseman   +11 more
openalex   +1 more source

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