Results 221 to 230 of about 8,099,068 (351)

Emerging investigator series: municipal wastewater as a year-round point source of neonicotinoid insecticides that persist in an effluent-dominated stream. [PDF]

Environ Sci Process Impacts, 2021
Webb DT, Zhi H, Kolpin DW, Klaper RD, Iwanowicz LR, LeFevre GH.   +5 more
europepmc   +1 more source

Potential of next-generation imaging spectrometers to detect and quantify methane point sources from space [PDF]

, 2019
Daniel Cusworth, Daniel Jacob, Daniel J. Varon, Christopher Chan Miller, Xiong Liu, K. Chance, Andrew K. Thorpe, Riley Duren, Charles E. Miller, David R. Thompson, Christian Frankenberg, Luis Guanter, Cynthia A. Randles   +12 more
openalex   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Pronounced transition of heavy metal pollution sources in Chinese agricultural surface waters: The rising prominence of non-point source pollution. [PDF]

iScience
Sui S, Wang M, Wang M, Ma W, Yang S, Zhang F, Jia L, Liu T.   +7 more
europepmc   +1 more source

Point-source burst of coordination polymer nanoparticles for tri-modality cancer therapy. [PDF]

Biomaterials, 2021
Ling X, Han W, Jiang X, Chen X, Rodriguez M, Zhu P, Wu T, Lin W.   +7 more
europepmc   +1 more source

Space-Time Folding of the Wake Produced by a Supervelocity Rotating Point Source

, 2019
Chloé d’Hardemare, Sander Wildeman, Antonin Eddi, Emmanuel Fort   +3 more
openalex   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Chip-Based Optoacoustic Single-Cell Detection in Flow Using Point-Source Optimized Surface Acoustic Wave Transducers. [PDF]

ACS Appl Mater Interfaces
Göllner S, Colditz M, Huang Y, Schmidt H, Winkler A, Stiel AC.   +5 more
europepmc   +1 more source

Distribution Characteristics and Risk Assessment of Agricultural Land Use Non-Point Source Pollution in Typical Biofuel Ethanol Planting Areas. [PDF]

Int J Environ Res Public Health, 2022
Cui G, Liu Y, Wang P, Bai X, Wang H, Xu Y, Xu Y, Yang M, Dong L.   +8 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source