Results 291 to 300 of about 8,099,068 (351)

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

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Photoacoustic Point Source

Physical Review Letters, 2001
Physical Review ...
I G, Calasso, W, Craig, G J, Diebold
openaire   +2 more sources

Pollution: Point Source

2016
Pollution can be generally defined as an undesirable change in the natural quality of the environment that may adversely affect the well being of humans, other living organisms, or entire ecosystems either directly or indirectly. Where pollution is localized
Ravendra Naidu, Mallavarapu Megharaj, Peter Dillon, Rai Kookana, Ray Correll, W.W. Wenzel   +5 more
openaire   +1 more source

Wavelength Discrimination for Point Sources

Journal of the Optical Society of America, 1958
Wavelength discrimination curves have been measured for two normal trichromats for three field sizes and various intensities. In order to obtain high-intensity levels in the blue region, a high-pressure xenon arc was used as a source. Results for the 1° field agree essentially with those of previous workers.
Bedford, R. E., Wyszecki, G. W.
openaire   +3 more sources

A POINT-SOURCE ASTHMA OUTBREAK

The Lancet, 1986
Epidemiological data for the eighth asthma epidemic in Barcelona were available from the whole city. They reveal a striking space clustering, an hour-time clustering, and simultaneous time and space clustering, which indicate that the outbreak was a point-source epidemic.
J M, Antó, J, Sunyer
openaire   +2 more sources

Point-like gamma-ray sources

Space Science Reviews, 1983
Various models are examined, which could give rise to point-like gamma-ray sources, at the present time indistinguishable, experimentally, from true point sources. These models involve energetic processes associated with interstellar clouds, e.g. supernova-cloud interactions, neutron star accretion inside interstellar clouds, cloud collisions, etc. The
G. E. Morfill, G. Tenorio-Tagle
openaire   +1 more source

Modeling for point–non-point source effluent trading: perspective of non-point sources regulation in China

The Science of The Total Environment, 2002
In the past decades, little abatement efforts have been implemented on China's non-point source water pollution, and studies aiming at non-point sources regulation were also rare. Watershed abatement trading between point and non-point sources may serve as a cost-effective way to deal with the problem.
W, Zhang, X J, Wang
openaire   +2 more sources

Non point source pollution

IGARSS '96. 1996 International Geoscience and Remote Sensing Symposium, 2002
Non Point Source (NPS) pollution is a major contributor to the degradation of surface water quality. NPS pollution is caused by water movement over and through the surface of the land. The runoff picks up and transports natural and man-made pollutants.
W. Subra, J. Waters
openaire   +1 more source