Results 181 to 190 of about 492,052 (313)

Telescope pointing for GOPEX

, 1993
In order for photons emitted by the GOPEX lasers to be detected by Galileo's camera, the telescopes at Table Mountain Observatory and Starfire Optical Range had to be pointed in the right direction within a tolerance less than the beam divergence.
Owen, W. M., Jr.
core  

Social communicative characteristics of adolescent police dogs: Acquired experience plays a crucial role. [PDF]

Anim Cogn
Huang X, Mei X, Wan K, Chen C, Wang L, Wang X, Wang GD.   +6 more
europepmc   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

Pointing: A Gesture that Makes Us Special?

Humana.Mente: Journal of Philosophical Studies, 2013
Massimiliano Lorenzo Cappuccio
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Pointing and Representing – Three Options

, 2013
The aim of this paper is to explore the minimal representational requirements for pointing. One year old children are capable of pointing – what does this tell us about their representational capacities?
Bence Nanay, Nanay, Bence, Angelica Kaufmann, Nick Young   +3 more
core  

MRSA mycotic aneurysm associated with infected pacemaker leads. [PDF]

IDCases
Weinstock A, To T, Rashid H, Sakamoto D, Hsei L, Patel K.   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

The Somatic Rubber Hand Illusion does not modulate perceived hand position in children with severe visual impairments. [PDF]

Sci Rep
Tammurello C, Coelho LA, Amadeo M, Setti W, Campus C, Signorini S, Morelli F, Cocchi E, Strazzer S, Tinelli F, Camicione P, Serafino M, Gori M.   +12 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source