Results 131 to 140 of about 2,491,773 (298)

Clinical Impact of NOTCH3 Variant Location After First Stroke in CADASIL

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Despite its monogenic origin, Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy exhibits marked variability in clinical expression and severity. Variants in the NOTCH3 gene, within epidermal growth factor‐like repeat domains 1–6 or 7–34, are known to influence disease onset, but their impact ...
Léa Aguilhon, Hugues Chabriat, Dominique Hervé, Stéphanie Guey, Sophie Tezenas Du Montcel, Juliette Ortholand   +5 more
wiley   +1 more source

Evaluation of Digital Technologies for Home‐Based Assessment in People With Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller, Vanessa Vallejo, Mónica Povedano Panadés, Orla Hardiman, Véronique Danel‐Brunaud, Senda Ajroud‐Driss, Philippe Couratier, Jeremy Shefner, Anna Gokey, Mike DiCesare, Erin Lennox, Jens Praestgaard, Lucie Brujin, Peggy Allred, Ram Miller   +14 more
wiley   +1 more source

High-Precision Pointing and Tracking System Design for Near-Space Balloon-Based Optical Observation

Applied Sciences
Near-space high-altitude balloon-based platforms have a series of advantages and provide superior conditions for optical observation. In order to ensure the stability of the optical axis of the optical detection load and stable tracking of the target, a ...
Lulu Qian, Min Huang, Wenhao Zhao, Yan Sun, Xiangning Lu, Zixuan Zhang, Guangming Wang, Yixin Zhao, Zhanchao Wang   +8 more
doaj   +1 more source

The VLT/ERIS vortex coronagraph: design, pointing control, and on-sky performance [PDF]

editorial reviewedThe Enhanced Resolution Imager and Spectrograph (ERIS) is the new near-infrared instrument at the VLT-UT4. ERIS replaces and extends the observational capabilities formerly provided by SINFONI and NACO: integral field spectroscopy at 1 -
Quanz, Sascha P., Huby, E., Grani, Paolo, Puglisi, Alfio, Grani, P., Bonse, Markus, Zins, Gérard, Glauser, Adrian M., Kenworthy, Matt, Dannert, F., Baruffolo, A., Absil, O., Hayoz, J., Glauser, A.M., Salasnich, Bernardo, Huby, Elsa, Puglisi, A., Bonse, M.J., Dannert, Felix, Davies, R., Quanz, S.P., Absil, Olivier, Baruffolo, Andrea, De Rosa, R.J., Kenworthy, M.A., Orban De Xivry, Gilles, Davies, Ric, Taylor, William, Hayoz, Jean, Salasnich, B., Taylor, W., De Rosa, Robert, Orban de Xivry, G., Zins, G.   +33 more
core   +1 more source

Sex‐Stratified Association of Regional Dopamine Transporter Binding With Disease Progression in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To clarify the clinical relevance of dopamine transporter single‐photon emission computed tomography (DAT‐SPECT) abnormalities in amyotrophic lateral sclerosis (ALS), with a prespecified focus on sex‐stratified associations with disease progression and short‐term prognosis.
Tomoya Kawazoe, Keizo Sugaya, Kentaro Hayashi, Keiko Hino, Yasuhiro Nakata, Kota Bokuda, Toshio Shimizu, Kazushi Takahashi   +7 more
wiley   +1 more source

Rapid acquisition of long spatial sequences in long-term memory [PDF]

, 2012
Learning complex movement sequences requires an active, attentional selection of the content that is learned. The selection mechanism can not be investigated in classical stimulus-guided sequence learning paradigms because it requires a movement sequence
Drever, Johannes
core   +1 more source

Nested task constraints shape continuous perception-action coupling control during human locomotor pointing

, 2004
Behavioural studies of human locomotor pointing have been dominated by specific task constraints of generating maximal approach velocity towards spatial targets.
Davids, Keith W., Renshaw, I, Davids, K, Renshaw, Ian   +3 more
core   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

A Digital Twin Model for Optical Telescope Pointing Systems

IEEE Photonics Journal
Pointing accuracy, as one of the important indexes to measure the performance of optical tele-scope products, is directly related to the observation quality and efficiency of the telescope, but affected by a variety of complex factors, the timeliness ...
Zhenghao Li, Yahui Zhang, Yan He
doaj   +1 more source

Alcohol, assault and licensed premises in inner-city areas [PDF]

, 2013
This report contains eight linked feasibility studies conducted in Cairns during 2010. These exploratory studies examine the complex challenges of compiling and sharing information about incidents of person-to-person violence in a late night ...
Charmaine S. Hayes-Jonkers, Alan R. Clough, Hayes-Jonkers, Charmaine S., Clough, Alan R., Edward S. Pointing, Pointing, Edward S.   +5 more
core