Results 71 to 80 of about 8,005 (245)

Trace Ru‐Doped PtCuRu@PtRu Core‐Shell Electrocatalyst for CO‐Resilient Methanol Oxidation

Advanced Science, EarlyView.
We engineered a trace Ru‐doped PtCuRu@PtRu core‐shell nanostructure. This design exploits lattice mismatch‐induced compressive strain between the PtCuRu ternary core and trace Ru‐doped Pt‐rich shell, systematically downshifting the Pt d‐band center to weaken *CO adsorption energetics.
Tianrui Xue, Shiyue Xing, Zhongliang Liu, Yiting Song, Jianyi Zhang, Miaomiao Liu, Huihui Li, Chunzhong Li   +7 more
wiley   +1 more source

Avaliação da rede brasileira de Centros de Controle de Intoxicações a Envenenamento - CCIEs

Cadernos de Saúde Pública
O crescimento dos registros das emergências causadas ou atribuídas à exposição de seres humanos e vários agentes tóxicos tornou imperiosa a avaliação do desempenho informacional da rede nacional de 34 centros de controle de intoxicações e envenenamentos (
Marília B. Marques, Maria Élide Bortoletto, Maria Cristina C. Bezerra, Rosane A. L. de Santana   +3 more
doaj  

Retrospective Review of Trend in Modafinil Overexposures Reported to American Poison Information Centers [PDF]

Asia Pacific Journal of Medical Toxicology, 2014
Background:Modafinil, a non-amphetamine central nervous system stimulant, is a wakefulness-promoting agent indicated for use in shift work sleep disorder, narcolepsy, and obstructive sleep apnea. The trend in modafinil overexposure over a ten-year period
Kristin Bohnenberger, Edward Krenzelok
doaj  

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Understanding the Catalytic Determinant role of Diaphorase‐Like Subunit in Formate Dehydrogenases via Redox Couples

Advanced Science, EarlyView.
A unique mechanism of catalytic bias regulated by diaphorase‐like subunit in formate dehydrogenase from Rhodobacter aestuarii is revealed. The diaphorase‐like subunit functions act as a biological “voltage rheostat” that controls the slow release of NADH to regulate redox balance, biasing the enzyme's catalytic preference toward CO2 reduction over ...
Kuncheng Zhang, Weisong Liu, Hao Su, Huijuan Cui, Yuanming Wang, Zhiguang Zhu, Chun You, Lingling Zhang   +7 more
wiley   +1 more source

Impacto dos medicamentos nas intoxicações humanas no Brasil

Cadernos de Saúde Pública
O presente trabalho analisa a participação dos medicamentos nas intoxicações humanas no Brasil, no período de 1993 a 1996, com base nos dados registrados pela Rede Nacional de Centros de Controle de Intoxicações.
Maria Élide Bortoletto, Rosany Bochner
doaj  

Intentional Recreational Abuse of Quetiapine Compared to Other Second-generation Antipsychotics

Western Journal of Emergency Medicine, 2017
Introduction: Case reports and poison center data have demonstrated that the second-generation antipsychotic quetiapine is being obtained and used for recreational abuse.
Lauren Klein, Stacey Bangh, Jon B. Cole
doaj   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

Advanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng, Wenxia Bu, Fengxu Wang, Yueyuan Jin, Rongzhu Liu, Rui Zhao, Xuehai Wang, Mengna Jiang, Jinping Shen, Xinhang Cheng, Zuming Chen, Li Zhu, Jinlong Li, Zhenzhong Ge, Shichen Miao, Haotian Xu, Xiaoyu Zhou, Dongming Wang, Xinyuan Zhao   +18 more
wiley   +1 more source

Lattice Distortion‐Driven Metal Exsolution in Perovskite Oxides

Advanced Science, EarlyView.
This study elucidates the mechanism of lattice distortion‐driven exsolution through a combination of computational simulations and experimental approaches. Lattice distortion facilitates the formation of oxygen vacancies and subsequent metal segregation, thereby enhancing the exsolution behavior.
Yo Han Kim, Uchan Jeon, Hyeongwon Jeong, Bo‐Ram Won, Jeong Woo Han, Jae‐ha Myung   +5 more
wiley   +1 more source

Metal‐Support Interaction Triggered Electronic Reconstruction in Pd/CoN‐Co4N Catalysts for Optimizing MEK Oxidation and Poisoning Resistance

Advanced Science, EarlyView.
The strengthened EMSI in Pd/CoN‐Co4N induces electronic rearrangement, generating abundant Pd0 species in situ, modulating the Pd d‐band center to enhance O2 adsorption and MEK activation. Concurrently, it creates numerous Lewis acid sites that preferentially adsorb poisons and shield the active sites.
Yadi Wang, Chaoqian Ai, Cai Wang, Zeyu Jiang, Jialei Wan, Jingjing Wang, Xiangbo Feng, Chi He   +7 more
wiley   +1 more source