Results 241 to 250 of about 3,820,327 (370)

Effects of Dictyophora polysaccharide on cerebellar Purkinje cell degeneration in a chronic alcohol mouse model

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In an ethanol (EtOH)‐treated mouse model, increases in the NLRP3 inflammasome proteins, PC degeneration, and motor coordination disorders were observed. DIP suppressed the NLRP3‐ASC‐caspase‐1 signaling pathway, and alleviated the motor deficits and cerebellar pathological changes in chronic EtOH‐treated mice.
Jian Zhang   +5 more
wiley   +1 more source

Description of Acute and Chronic Cases of Poisoning by <i>Oxalis pes-caprae</i>. [PDF]

open access: yesAnimals (Basel)
Pinna L   +6 more
europepmc   +1 more source

A hepatoprotective experiment on taro vegetable (Colocasia esculenta (L.) Schott) flower employing animal models by mitigating oxidative stress

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The antioxidant efficacy of Colocasia esculenta flower’s methanolic extract was assessed using 2,2′‐azino‐bis‐(3‐ethylbenzothiazoline‐6‐sulfonic) (ABTS) and 2,2‐diphenyl‐1‐picrylhydrazyl (DPPH) scavenging assay. The hepatoprotective effect was investigated by assessing liver injury indicators (amino transferase [ALT], aspartate amino transferase [AST],
Mahathir Mohammad   +9 more
wiley   +1 more source

Metal‐Responsive Up‐Regulation of Bifunctional Disulfides for Suppressing Protein Misfolding and Promoting Oxidative Folding

open access: yesAngewandte Chemie, EarlyView.
A stress‐responsive folding promotor was developed by conjugating metal‐binding ligands and a redox‐active disulfide. The oxidative strength of the bifunctional disulfide was enhanced by metal coordination, inhibiting protein misfolding and up‐regulating the oxidative folding capacity under metal stress.
Keita Mori   +8 more
wiley   +2 more sources

A Drosophila model of prion disease and its metabolic changes in the brain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We developed a Drosophila model for prion disease, and flies were capable of expressing the hamster prion protein (HaPrP) under the control of the GAL4/UAS system. The model exhibited some characteristics of the disease in mammals and displayed alterations in protein, sphingolipid, and carbohydrate metabolism. Preliminary applications have demonstrated
Dongdong Wang   +14 more
wiley   +1 more source

Linking Metallacycle Transfer with Ring‐Opening Metathesis to Generate Polyacetylenes of Unprecedented Structure

open access: yesAngewandte Chemie, EarlyView.
A series of unusual low HOMO‐LUMO gap polyacetylenes bearing ring‐fused tellurophene and vinyl side chains were prepared by combining metallacycle transfer (Hf/p‐block element exchange) with ring‐opening metathesis polymerization (ROMP) into a single modular and efficient protocol.
Abhishek V. Muralidharan   +2 more
wiley   +2 more sources

Poisonous Natural Plants

open access: yesFood Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 2011
openaire   +3 more sources

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