Bufalin Inhibits the PI3K/AKT Pathway by Targeting GTF3C4 to Impede Breast Cancer Progression
Mechanisms of Bufalin‐Mediated Intervention in Breast Cancer. ABSTRACT Breast cancer incidence is rising globally, presenting challenges such as treatment side effects and drug resistance. Bufalin is a bufadienolides compound with potential anti‐cancer effects. This study shows that bufalin inhibits malignant proliferation of MDA‐MB‐231 and MCF‐7 cells
Siyu Guo +15 more
wiley +1 more source
VAM-Based Equivalent Cauchy Model for Accordion Honeycomb Structures with Zero Poisson's Ratio. [PDF]
Lin Y +5 more
europepmc +1 more source
A new class of biohybrid spheroids is engineered through the self‐assembly of adherent cells and extracellular matrix‐mimetic hydrogel microparticles (microgels). By mimicking a snowballing effect, this approach enables scalable formation of porous, millimeter‐scale spheroids with enhanced cell viability and molecular diffusion.
Zaman Ataie +7 more
wiley +1 more source
Investigating the Effects of Surface Texture Direction and Poisson's Ratio on Stress Concentration Factors. [PDF]
Liu Y, Liu Y, Cheng Z.
europepmc +1 more source
Optimization of neural-network model using a meta-heuristic algorithm for the estimation of dynamic Poisson's ratio of selected rock types. [PDF]
Waqas U +3 more
europepmc +1 more source
A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim +12 more
wiley +1 more source
Theoretical stress mechanism and structural integrity of viscoelastic propellant grains with variable Poisson's ratio. [PDF]
Wang X +5 more
europepmc +1 more source
Inversion Method of the Young's Modulus Field and Poisson's Ratio Field for Rock and Its Test Application. [PDF]
Yin Y +5 more
europepmc +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source

