Results 261 to 270 of about 6,540,164 (372)

3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures

open access: yesAdvanced Science, EarlyView.
This study developed a 3D brain vascular niche model that capture the key features of glioblastoma including perivascular infiltration, gene signature, dormancy and chemo resistance, by comparing 3D model with in vivo condition using identical glioma stem cells.
Vivian K. Lee   +10 more
wiley   +1 more source

Piezo1 Activation Improves NSCLC Liver Metastasis Immunotherapy by Overriding Matrix Stiffness‐Mediated Bimodal PD‐L1/CXCL10 Regulation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Piezo1 activation enhances FAK‐YAP‐mediated upregulation of PD‐L1 and CXCL10, thereby promoting an immunotherapy‐responsive tumor microenvironment in NSCLC. Cyclic stretch modulates the PD‐L1/CXCL10 response to ECM stiffness, reshaping their expression dynamics.
Tian Zhang   +11 more
wiley   +1 more source

Bacteria Optimize Tumble Bias to Strategically Navigate Surface Constraints

open access: yesAdvanced Science, EarlyView.
The study investigates how Escherichia coli optimizes tumble bias (TB) to navigate surface constraints effectively. Using single‐cell tracking and modeling, it reveals that bacterial surface residence time decreases with increasing TB, stabilizing near the wild‐type mean TB (≈0.25), where surface diffusivity peaks.
Antai Tao   +3 more
wiley   +1 more source

Reconstructing Three‐Dimensional Optical Anisotropy with Tomographic Müller‐Polarimetric Microscopy

open access: yesAdvanced Science, EarlyView.
Tomographic Müller polarimetric microscopy is a novel imaging technique that resolves 3D birefringent properties of bulky samples, unveiling hierarchical nanostructures at microscopic resolution. Based on incoherent visible‐light polarimetry, it achieves experimental simplicity by eliminating phase measurements.
Yang Chen   +4 more
wiley   +1 more source

Phenotype driven data augmentation methods for transcriptomic data. [PDF]

open access: yesBioinform Adv
Janakarajan N   +2 more
europepmc   +1 more source

Nano‐Oil‐Barrier‐Based Fluttering Triboelectric Nanogenerator

open access: yesAdvanced Science, EarlyView.
This work proposes a wind‐driven nano‐oil‐barrier‐based fluttering triboelectric nanogenerator (NF‐TENG). A nano‐oil barrier is a simple and innovative strategy to maintain a thin lubricant layer for long‐term cycling based on commercial oil‐absorbing sheets and oil‐infusion steps, which can improve both mechanical and electrical stability of TENGs ...
Deokjae Heo   +8 more
wiley   +1 more source

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