Results 41 to 50 of about 2,565,964 (296)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Modified Ridge Estimator for Poisson Regression

Cumhuriyet Science Journal
Poisson regression is a statistical model used to model the relationship between a count-valued-dependent variable and one or more independent variables. A frequently encountered problem when modeling such relationships is multicollinearity, which occurs
Shuaib Mursal Ibrahim, Aydın Karakoca
doaj   +1 more source

Modelling fertility levels in Nigeria using Generalized Poisson regression-based approach

Scientific African, 2020
The rapid increase in total children ever born without a proportionate growth in the Nigerian economy has been a major concern. The total children ever born, being a count data, requires applying an appropriate regression model.
Jecinta U. Ibeji, Temesgen Zewotir, Delia North, Lateef Amusa   +3 more
doaj   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

POISSON REGRESSION MODELS TO ANALYZE FACTORS THAT INFLUENCE THE NUMBER OF TUBERCULOSIS CASES IN JAVA

Barekeng, 2023
Tuberculosis is an infectious disease and one of the world's top 10 highest causes of mortality in Indonesia. Based on this fact, it is necessary to study what factors affect number of tuberculosis cases.
Yekti Widyaningsih, Zalfa Alifah Budiawan   +1 more
doaj   +1 more source

Poisson inverse problems [PDF]

, 2006
In this paper we focus on nonparametric estimators in inverse problems for Poisson processes involving the use of wavelet decompositions. Adopting an adaptive wavelet Galerkin discretization, we find that our method combines the well-known theoretical ...
Antoniadis, Anestis, Bigot, Jérémie
core   +1 more source

Retractions in Rheumatology: Trends, Causes, and Implications for Research Integrity

Arthritis Care &Research, EarlyView.
Objective We aimed to describe the trends and main reasons for study retraction in rheumatology literature. Methods We reviewed the Retraction Watch database to identify retracted articles in rheumatology. We recorded the main study characteristics, authors’ countries, reasons for retraction, time from publication to retraction, and trends over time ...
Anna Maria Vettori, Michele Iudici
wiley   +1 more source

Modelling Negative Binomial as a substitute model to Poisson for raters agreement on ordinal scales with sparse data [PDF]

, 2004
The Poisson distribution has been widely used for modelling rater agreement using loglinear models. Mostly in all life or social science researches, subjects are being classified into categories by rater, interviewers or observers and most of these ...
Toutenburg, Helge, Heumann, Christian, Adejumo, A. O.   +2 more
core   +1 more source