Results 211 to 220 of about 160,640 (261)
Pathogenic Variants in Mennonites From Southern Brazil: Implications for Preventive Measures in Public Health
Clinical Genetics, Volume 109, Issue 2, Page 266-276, February 2026.In 325 exomes of South Brazilian Mennonites, we identified 23 pathogenic variants (P) and 27 likely P, with founder effects identified for 96% of P, whose frequencies differed from non‐Finnish Europeans, Amish, and Brazilian populations. ABSTRACT
The Mennonite population has a unique history of 500 years of genetic isolation shaped by at least three ...Luiza Beatriz Mayer de Lima, Eduardo Delabio Auer, Isabela Dall’Oglio Bucco, Valéria Bumiller‐Bini Hoch, Priscila Ianzen dos Santos, Fabiana L. Lopes, Alan Shuldiner, Emilton Lima Júnior, Angelica Beate Winter Boldt +8 morewiley +1 more sourcePharmacogenomics of Thiopurine Drugs: A Bench‐To‐Bedside Success Story in Thailand
Clinical and Translational Science, Volume 19, Issue 2, February 2026.ABSTRACT
Thiopurine drugs are the cornerstone treatment for many diseases such as acute lymphoblastic leukemia (ALL), organ rejection, inflammatory bowel disease (IBD), systemic lupus erythematosus (SLE), rheumatoid arthritis (RA) and other autoimmune diseases.Mohitosh Biswas, Shobana John, Murshadul Alam Murad, Chonlaphat Sukasem +3 morewiley +1 more sourceBeyond the Usual Suspects: RSV Infection in Patients With Hematological Malignancies Compared to Influenza and SARS‐COV‐2—A Report From the EPICOVIDEHA/EPIRESEHA Registry
American Journal of Hematology, Volume 101, Issue 2, Page 365-375, February 2026.Jon Salmanton‐García, Francesco Marchesi, Milan Navrátil, Iker Falces‐Romero, Maria Ilaria Del Principe, Jorge Labrador, Klára Piukovics, Verena Petzer, Monika M. Biernat, Michail Samarkos, Dario Leotta, Nicola Fracchiolla, Anna Dąbrowska‐Iwanicka, Antonio Vena, Benjamín Víšek, Yavuz M. Bilgin, Jens Van Praet, Mario Virgilio Papa, Inmaculada Heras Fernando, Francesca Farina, Ľuboš Drgoňa, Josip Batinić, Barbora Weinbergerová, Nurettin Erben, Joanna Drozd‐Sokołowska, Patricia García‐Ramírez, Annarosa Cuccaro, Martin Čerňan, Nicola Sgherza, Tobias Lahmer, Donald C. Vinh, Gaëtan Plantefeve, Alberto López‐García, Chiara Cattaneo, Nikola Pantić, Sofya Khostelidi, Julio Dávila‐Valls, Andrés Soto‐Silva, László Imre Pinczés, Ferenc Magyari, Reham Abdelaziz Khedr, Michelina Dargenio, Martijn Bakker, Igor Stoma, Carolina Garcia‐Vidal, Ildefonso Espigado, Claudio Cerchione, Caterina Buquicchio, Zlate Stojanoski, Gabriele Magliano, Stefanie K. Gräfe, Avinash Aujayeb, Lucia Prezioso, Vladimir Otašević, Maria Merelli, Erica Mackenzie, Andreas Glenthøj, Eleni Gavriilaki, Noha Eisa, Mario Delia, Alessandro Busca, Ahlam Almasari, Tatjana Adžić‐Vukičević, Ivana Urošević, Uluhan Sili, Carolina Miranda‐Castillo, Gustavo‐Adolfo Méndez, Stef Meers, Monia Marchetti, Nicola Coppola, Gökçe Melis Çolak, Darko Antić, Ditte Stampe Hersby, Pellegrino Musto, Milche Cvetanoski, Martin Schönlein, Tommaso Francesco Aiello, Elena Arellano, Davide Nappi, Sonia Martín‐Pérez, Mirjana Mitrović, Raul Cordoba, Romane Prin, Marta Callejas‐Charavia, Gina Varricchio, Martina Bavastro, Alessandro Limongelli, Amalia N. Anastasopoulou, Alessandra Romano, Dominik Wolf, Kevin Nguyen, Lukas Van Den Ven, Alessia Di Pilla, Antonio Giordano, Oliver A. Cornely, Livio Pagano +95 morewiley +1 more sourceAssessing the independent and combined impact of obesity and gestational diabetes mellitus on adverse maternal outcomes: A systematic review and meta‐analysis
Diabetic Medicine, Volume 43, Issue 2, February 2026.Abstract Aims
To evaluate the impact of obesity, with or without gestational diabetes mellitus (GDM), on adverse maternal outcomes and determine whether the combination of obesity and GDM confers a greater risk compared to obesity alone. Methods
We systematically searched MEDLINE, EMBASE, Scopus, CINAHL and the WoS Core Collection, identifying 19 ...Tessa L. Weir, Monica Majumder, Sarah J. Glastras +2 morewiley +1 more sourceAssociations of modifiable preconception, pregnancy and postpartum factors with health outcomes for women with type 2 diabetes and their children: A systematic review and meta‐analysis of observational studies
Diabetic Medicine, Volume 43, Issue 2, February 2026.Abstract Aim
Type 2 diabetes (T2D) in pregnancy is increasingly common and associated with suboptimal outcomes for these women and their children. We aimed to synthesize observational evidence on associations of modifiable preconception, pregnancy and postpartum risk factors with perinatal outcomes among women with pregestational T2D.Danielle Schoenaker, Eleanor Dyer, Nicola Heslehurst, Grainne Kent, Sowmiya Gunabalasingam, Lily Hopkins, Artemis Kyrka, Rivka Lebrett, Angela C. Flynn, Sara L. White, Claire L. Meek, Rita Forde +11 morewiley +1 more sourceBaseline characteristics in the SYNCHRONIZE™‐2 randomized phase 3 trial of survodutide, a glucagon receptor/GLP‐1 receptor dual agonist, for obesity in people with type 2 diabetes
Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1490-1498, February 2026.Abstract Aims
Survodutide is an investigational glucagon receptor/glucagon‐like peptide‐1 receptor dual agonist that has shown promise for treating obesity and its complications in Phase 2 trials. Two double‐blind, randomized, global Phase 3 trials are designed to assess the efficacy and safety of survodutide for treatment of obesity—SYNCHRONIZE™‐1 in ...Sean Wharton, Carel W. le Roux, Biykem Bozkurt, Elke Platz, Gabriele Bleckert, Samina Ajaz Hussain, Martina Brueckmann, Elena Startseva, Isabel M. Kloer, Lee M. Kaplan +9 morewiley +1 more source
