Results 71 to 80 of about 84,554 (258)
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Implementation of the Polar Code: Functional Requirements Regulating Ship Operations in Polar Waters
Arctic Review on Law and Politics, 2020 In 2017, the The International Code for Ships Operating in Polar Waters (Polar Code) – a set of function-based regulations applicable to Arctic and Antarctic waters, with the goal of increasing awareness and improving safety for ship operations in polar ...
Espen Engtrø +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Partially Information Coupled Polar Codes
IEEE Access, 2018 We propose a new class of partially information coupled (PIC) polar codes to improve the transmission efficiency of transport block (TB)-based communication standards.
Xiaowei Wu +3 more
doaj +1 more source
IET Communications, 2021 In this study, a coded cooperation scheme using polar codes is explored for high‐reliability and low‐user complexity applications such as Internet of Things.
Hao Liang +4 more
doaj +1 more source
CoRR7 pages, 7 figures and 2 tables; A short version will be submitted to IEEE for possible ...
Ling Liu 0003 +3 more
openaire +2 more sources
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Distributed Joint Source-Channel Coding Using Quasi-Uniform Systematic Polar Codes
Entropy, 2018 This paper proposes a distributed joint source-channel coding (DJSCC) scheme using polar-like codes. In the proposed scheme, each distributed source encodes source message with a quasi-uniform systematic polar code (QSPC) or a punctured QSPC, and only ...
Liqiang Jin, Hongwen Yang
doaj +1 more source
Multilevel polar-coded modulation [PDF]
2013 IEEE International Symposium on Information Theory, 2013 A framework is proposed that allows for a joint description and optimization of both binary polar coding and the multilevel coding (MLC) approach for $2^m$-ary digital pulse-amplitude modulation (PAM). The conceptual equivalence of polar coding and multilevel coding is pointed out in detail. Based on a novel characterization of the channel polarization
Mathis Seidl +3 more
openaire +2 more sources