Results 61 to 70 of about 87,888 (259)

The International Code for Ships Operating in Polar Waters: Finalization, Adoption and Law of the Sea Implications

open access: yesArctic Review on Law and Politics, 2016
The most recent instrument specifically designed to make navigation in polar waters safer and more environmentally friendly is the International Maritime Organization's long-awaited “International Code for Ships Operating in Polar Waters” – the Polar ...
Øystein Jensen
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

Blind Detection With Polar Codes [PDF]

open access: yesIEEE Communications Letters, 2017
In blind detection, a set of candidates has to be decoded within a strict time constraint, to identify which transmissions are directed at the user equipment. Blind detection is an operation required by the 3GPP LTE/LTE-Advanced standard, and it will be required in the 5th generation wireless communication standard (5G) as well.
Carlo Condo   +2 more
openaire   +2 more sources

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Convolutional Polar Codes

open access: yesCoRR, 2017
Arikan's Polar codes attracted much attention as the first efficiently decodable and capacity achieving codes. Furthermore, Polar codes exhibit an exponentially decreasing block error probability with an asymptotic error exponent upper bounded by 1/2. Since their discovery, many attempts have been made to improve the error exponent and the finite block-
Andrew James Ferris   +2 more
openaire   +2 more sources

List decoding of polar codes [PDF]

open access: yes2011 IEEE International Symposium on Information Theory Proceedings, 2011
We describe a successive-cancellation \emph{list} decoder for polar codes, which is a generalization of the classic successive-cancellation decoder of Arıkan. In the proposed list decoder, up to $L$ decoding paths are considered concurrently at each decoding stage. Then, a single codeword is selected from the list as output. If the most likely codeword
Ido Tal, Alexander Vardy
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Design and Optimization of Joint Iterative Detection and Decoding Receiver for Uplink Polar Coded SCMA System

open access: yesIEEE Access, 2018
SCMA and polar coding are possible candidates for 5G systems. In this paper, we firstly propose the joint iterative detection and decoding (JIDD) receiver for the uplink polar coded sparse code multiple access (PC-SCMA) system.
Zhipeng Pan   +4 more
doaj   +1 more source

Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology

open access: yesMolecular Oncology, EarlyView.
This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic   +15 more
wiley   +1 more source

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