Results 51 to 60 of about 84,640 (256)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Blind Detection With Polar Codes [PDF]

open access: yesIEEE Communications Letters, 2017
In blind detection, a set of candidates has to be decoded within a strict time constraint, to identify which transmissions are directed at the user equipment. Blind detection is an operation required by the 3GPP LTE/LTE-Advanced standard, and it will be required in the 5th generation wireless communication standard (5G) as well.
Carlo Condo   +2 more
openaire   +2 more sources

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

List decoding of polar codes [PDF]

open access: yes2011 IEEE International Symposium on Information Theory Proceedings, 2011
We describe a successive-cancellation \emph{list} decoder for polar codes, which is a generalization of the classic successive-cancellation decoder of Arıkan. In the proposed list decoder, up to $L$ decoding paths are considered concurrently at each decoding stage. Then, a single codeword is selected from the list as output. If the most likely codeword
Ido Tal, Alexander Vardy
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Polar Grassmannians and their Codes

open access: yesCoRR, 2015
This is a copy of the Extended Abstract accepted for presentation at MEGA2015 in ...
Ilaria Cardinali, Luca Giuzzi
openaire   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Convolutional Polar Codes

open access: yesCoRR, 2017
Arikan's Polar codes attracted much attention as the first efficiently decodable and capacity achieving codes. Furthermore, Polar codes exhibit an exponentially decreasing block error probability with an asymptotic error exponent upper bounded by 1/2. Since their discovery, many attempts have been made to improve the error exponent and the finite block-
Andrew James Ferris   +2 more
openaire   +2 more sources

Design and Optimization of Joint Iterative Detection and Decoding Receiver for Uplink Polar Coded SCMA System

open access: yesIEEE Access, 2018
SCMA and polar coding are possible candidates for 5G systems. In this paper, we firstly propose the joint iterative detection and decoding (JIDD) receiver for the uplink polar coded sparse code multiple access (PC-SCMA) system.
Zhipeng Pan   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

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