Results 161 to 170 of about 2,727,646 (335)

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Polar vortex weakening and its impact on surface temperature in recent decades

The stratospheric polar vortex (SPV) weakening is linked to surface circulation changes. This study employs statistical analysis using reanalysis data to compare the anomalous SPV behaviour in the Northern (NH) and Southern (SH) hemispheres and its ...
Kim, Seong-Joong, Choi, Hyesun
core   +1 more source

BOOK REVIEW: Review of Tourism and change in polar regions: climate, environment and experience and Cruise tourism in polar regions: promoting environmental and social sustainability?

, 2011
These two edited volumes, which cover much of the same ground, both begin from a common premise: polar tourism, as its been experienced by wealthy travellers for over a century, has a very definite shelf life.
P.J. Capelotti, Capelotti, P. J.
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Review of Scott’s last biscuit: the literature of polar exploration, by Sarah Moss

, 2007
Fifty years ago, George Bass revolutionized maritime archaeology with the observation that it was far simpler to train an archaeologist to be a scuba diver than it was to turn a scuba diver into an underwater archaeologist.
Capelotti, P. J.
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Adaptations and lifestyle in polar marine environments: a biological challenge for the study of fish evolution

, 2004
The climatic features of Antarctic waters are more extreme and constant than in the Arctic. The Antarctic has been isolated and cold longer than the Arctic.
Parisi, Elio, Cocca, Ennio, de Pascale, Donatella, di Frisco, Guido, Verde, Cinzia   +4 more
core   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

FEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno, Shota Yamazaki, Hiromichi Hoshina, Masahiko Harata   +3 more
wiley   +1 more source

In memory of Torgny Vinje—a genuine polar scientist

, 2016
No abstract available.(Published: 31 May 2016)Citation: Polar Research 2016, 35, 32211,http://dx.doi.org/10.3402/polar.v35 ...
Gerland, Sebastian, Elisabeth Isaksson, Divine, Dmitry, Isaksson, Elisabeth, Dmitry Divine, Sebastian Gerland   +5 more
core   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source